肝移植术后停用免疫抑制剂1例分析

吕国悦; 王传磊; 孙晓东; 邱伟; 杜晓宏; 张威; 王广义

doi:10.3969/j.issn.1001-5256.2013.09.020

肝移植术后停用免疫抑制剂1例分析

DOI: 10.3969/j.issn.1001-5256.2013.09.020

吉林大学白求恩第一医院肝胆胰外科

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中图分类号: R657.3
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出版历程
- 出版日期: 2013-09-20

Discontinuation of immunosuppressive therapy after liver transplantation: an analysis of one case

Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University

摘要

摘要: <正>1临床资料患者,男,52岁,因皮肤巩膜黄染4个月,全身乏力2个月于2003年6月2日入院,既往:2001年3月因门脉高压行脾切除、贲门周围血管离断术,临床诊断为:乙型肝炎肝硬化、肝功能失代偿。入院后行改善肝功能、全身状态及凝血功能治疗,之后于2003年6月20日行同种异体原位肝移植术,供肝热缺
- 肝移植 /
- 免疫抑制剂 /
- 免疫耐受
- liver transplantation /
- immunosuppressive agents /
- immune tolerance

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参考文献(13)

[1]DESAI M, NEUBERGER J.Chronic liver allograft dysfunction[J].Transplant Proc, 2009, 41 (2) :773-776.

[2]SAWADA T, ASANUMA Y, FURUGA T, et al.Induction of systemic tolerance in islet allograft by liver transplantation[J].Transplant Proc, 2001, 33 (6) :2995-2999.

[3]BILLINGHAM RE, BRENT L, MEDAWAR PB.Actively acquired tolerance of foreign cells[J].Nature, 1953, 172 (4397) :603-606.

[4]WIEERS G, GRAS J, BOURDEAUX C, et al.Monitoring tolerance after human liver transplantation[J].Transpl Immunol, 2007, 17 (2) :83-93.

[5]STARZL TE, DEMETRIS AJ, TRUCCO M, et al.Cell migration and chimerism after whole-organ transplantation:The basis of graft acceptance[J].Hepatology, 1993, 17 (6) :1127-1152.

[6]MAZARIEGOS GV, REYES J, MARINO IR, et al.Weaning of immunosuppression in liver transplant recipients[J].Transplantation, 1997, 63 (2) :243-249.

[7]TAKATSUKI M, UEMOTO S, INOMATAT Y, et al.Weaning of immunosuppression in liver donor liver transplant recipients[J].Transplantation, 2001, 72 (3) :449-454.

[8]GIRLANDA R, RELA M, WILLIAMS R, et al.Long-term outcome of immunosuppression with drawal after liver transplantation[J].Transplant Proc, 2005, 37 (4) :1708-1709.

[9]EASON JD, COHEN AJ, NAIR S, et al.Tolerance:is it worth the risk?[J].Transplantation, 2005, 79 (9) :1157-1159.

[10]TISONE G, ORLANDO G, CARDILLO A, et al.Complete weaning off immunosuppression in HCV liver transplant recipients is feasible and favourably impacts on the progression of disease recurrence[J].J Hepatol, 2006, 44 (4) :702-709.

[11]FNDRICH F.Tolerance in clinical transplantation:progress, challenge or just a dream?[J].Langenbecks Arch Surg, 2011, 396 (4) :475-487.

[12]LI JZ.Cellular and molecular mechanisms in liver transplantion tolerance[J].Inter J Immunol, 2009, 32 (2) :117-120. (in Chinese) 李金政.肝脏移植耐受细胞分子机制研究进展[J].国际免疫学杂志, 2009, 32 (2) :117-120.

[13]LI JQ, ZHOU JY.The role of immune cells in immune tolerance mechanisms towards chronic hepatitis B[J].J Clin Hepatol, 2011, 27 (4) :437-440. (in Chinese) 李俊卿, 周俊英.免疫细胞在慢性乙型肝炎免疫耐受机制中的作用[J].临床肝胆病杂志, 2011, 27 (4) :437-440.

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