TTV阳性肝病患者的临床特征

谭欣诚; 王云; 张希成; 刘志华; 李小平; 王乐农

TTV阳性肝病患者的临床特征

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出版历程
- 出版日期: 2000-04-20

The clinical characters of Transfusion transmitted virus positive hepatitis patients

摘要

摘要: 观察TTV(Transfusiontransmittedvirus,TTV)阳性肝病患者的临床特征。用巢式PCR法检测血清TTVD NA ,同时观察血清生化指标和肝组织学的变化。TTV感染者的血清学模式以HBV、HCV、HAV、HEV混合感染为主 ,占 6 1.1% ( 2 2 /36 ) ,临床表现以乏力、纳差为特征 ,TBL、ALT变化不明显 ;而TTV单独感染者为 38.9% ( 14/36 )临床特征与急性黄疸性肝炎相似。TTV可与各型已知肝炎病毒混合感染 ,可呈隐匿性发病。
- 肝病 /
- 输血传播病毒 /
- 临床特征
Abstract: To investigate the clinical Characters of patients with transfusion transmitted virus (TTV) positive hepatosis.The ased in this article are examination of TTV DNA by nested PCR observation of serum biochemical substance and chanage of hepatohistology.TTV positive patients were shoed dominantly coinfected with HBV, HCV, HAV and HEV counted up to 61.1% (22/36) ;A clinical features were weak and poor appetite;the chang of TBL and ALT is not remarkable;patients only infect with TTV accounted for 38.9 (14/36) and their clinical manifestations were similar with acute jaundice hepatitis.TTV may coinfected with various hepatitis virus.The attack of TTV positive hepatitis were a bidden course.Those also may be infected only TTV, or sometime a clinical symptoins were serious, TBL and ALT were abnormal significantly, and ALT repeatedly.
- Liver disease /
- Transfusion transmitted virus /
- Clinical characters

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参考文献(3)

[]〔1〕周伯平 , 马为民 , 孙彤 , 等 .TTV在非甲～庚型肝炎患者的检测、克隆及测序〔J〕 .中华传染病杂志 , 1998, 3 (16 ) ∶131.

[]〔2〕魏来 , 陶其敏 , 潘修成 , 等 .TT病毒核酸的检测〔J〕 .中华医学检验杂志 , 1998, 5 (2 1) 2 75 .

[]〔3〕OKamotoH , NishizawaT , KatoN , etal.molecularcloningandcharac treizationofanovelDNAVirus (TTV) associatedwthposttransfusionhepati tisofunknownetioligy〔J〕 .HepatolRes, 1998, 10∶1.

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