Abstract: WT5”BZ]There are a variety of digestive symptoms such as upper abdominal pain, early satiety, nausea, vomitting and heart burn in patients with cirrhosis or liver cancer In order to understand the mechanism of above mentioned symptoms further we have investigated the gastric liquid emptying in 20 normal volunteers and 50 patients with cirrhosis or liver cancer by B mode ultrasonography and the promoting effect of singledose cisapride The results show that the half gastric emptying time (T1/2) is 13 90±4 30 min in normal subjects and 39 36±12 30 min in patients with cirrhosis, 40 50±8 91 min in patients with liver cancer A significantly delayed gastric emptying was found in patients with cirrhosis or liver cancer comparing with control subjects (P<0 05) The T1/2 in patients can be shortened to 24 37±11 37 min after administration with 10 mg cisapride (P<0 05) All data indicate that the severely delayed gastric emptying in patients with chronic liver diseases is one of explanations of the digestive symptoms in the patients and cisapride is very useful for relieving patients from pain [WT5”HZ]