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Evaluation of Serum β2-microglobulin in differential diagnosis of hepatocarcinoma
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摘要: 探讨血清 β2 -MG在原发性肝癌鉴别诊断中的价值。采用放射免疫法测定正常人、肝癌、肝硬化、肝血管瘤患者血清中 β2 -MG ,AFP的含量。肝癌患者 β2 -MG含量高于正常人、肝硬化、肝血管瘤患者。肝血管瘤患者与正常人血清 β2 -MG含量无明显差别。肝硬化患者血清 β2 -MG含量高于正常人 ,炎症型肝癌患者血清 β2 -MG含量高于单纯型、硬化型患者 ,血清 β2 -MG与AFP无相关关系。血清 β2 -MG是与AFP无关的、独立的肿瘤标记物 ,有助于肝癌、肝硬化、肝血管瘤的鉴别诊断。Abstract: To study the evaluation of serum β 2-MG in differential diagnosis of hepatocarcinoma. By using RIA, the levels of serum β 2-MG and AFP of the health adults, patients with hepatocarcinoma, liver cirrhosis (LC) and hepatic hemangioma are examined. Serum β 2-MG levels of hepatocarcinoma are higher than that of the health adults, patients with LC and patients with hepatic hemangioma. In health adults and patients with hepatic hemangioma there is no significantly difference of β 2-MG. Serum β 2-MG Levels of patients with LC are higher than that of the health adults. And levels of inflammatory type cases are significantly higher than that of simple type and cirrhotic type cases in hepatocarcinoma. There is no relationship between Serum β 2-MG and AFP. Serum β 2-MG is a singly tumor marker and has no relationship with AFP. The examination of serum β 2-MG is helpful to the differential diagnose in hepatocarcinoma, LC and hepatic hemangioma.
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Key words:
- Hepatocarcinoma /
- β 2-microglobulin /
- Differential diagnosis
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