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肝纤维化的基因治疗现状

陈莎燕 曾令兰

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肝纤维化的基因治疗现状

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  • 中图分类号: R575.2

  • [1]Song YH, Chen XL, Kong XL, et al.Ribozymes against TGF beta 1reverse character of activated hepatic stellate cells in vitro and inhibitliver fibrosis in rats[J].Ournal of Gene Medicine, 2005, 7 (7) ∶965-976.
    [2]Qi Z, Atsuchi N, Ooshima A, et al.Blockade of type beta transfor-ming growth factor si gnaling preventing liver fibrosis and dysfunctionin the rat[J].Proc Natl Acad Sci, 1999, 96∶2345-2349.
    [3]Inagaki Y, Kushida M, Higashi K, et al.Cell type-specific inter-vention of transforming growth factor beta/smad signaling supressescollagen gene expression and hepatic fibrosis in mice[J].Gastroen-terology, 2005, 129 (1) ∶295-68.
    [4]Suzuki K, Aoki K, Ohnami S, et al.Adenovirus-mediated genetransfer of interferon alpha improves dimethylnitrosamine-inducedliver cirrhosis in rat model[J].Gene Ther, 2003∶765-773.
    [5]Xia JI, Dai C, Michalopoulos GK, et al.Hepatocyte growth factorattenuates liver fibrosis induced by bile duct ligation[J].Am JPathol, 2006, 168 (5) ∶1500-12.
    [6]Xue F, Takahara T, Yata Y, et al.Hepatocyte growth factor genetherapy accelerates regen eration in cirrhotic mouse livers after hepatectomy[J].Gut, 2003, 52∶694-700.
    [7]Iimuro Y, Nishio T, Morimoto T, et al.Delivery of matrix metalloproteinase-1 attenuates established liver fibrosis in the rat[J].Gastroenterology, 2003, 124∶445-458.
    [8]Siller-Lopen F, Sandoval A, Salgado S, et al.Treatment With Hu-man Metalloproteinase-8 Gene Delivery Ameliorates ExperimentalRat Liver Cirrhosis[J].Gastroenterology, 2004, 126∶1122-1133.
    [9]Zhang LH, Pan JP, Yao HP, et al.Intrasplenic transplantation of IL-18 gene-modified hepatocytes:an effective approach to reversehepatic fibrosis in schistosomiasis through induction of dominant Th1response[J].Gene Ther, 2001, 8∶1333-1342.
    [10]Wang CH, Lee TH, Lu CN, et al.Eletroporative alpha-MSHgene transfer attenuates thioacetamide-induced murine hepatic fi-brosis by MMP and TIMP modulation[J].Gene Ther, 2006, 13 (13) ∶1000-9.
    [11]Miranda-Diaz A, Rincon AR, Salgado S, et al.Improved effectsof viral gene delivery of human uPA plus biliodigestive anastomosisinduce recovery from experimentalbiliary cirrhosis[J].Mol Ther, 2004, 9∶30-37.
    [12]Rudolph KL, Chang S, Millard M, et al.Inhibition of experimentalliver cirrhosis in mice by telomerase gene delivery[J].Science, 2000, 287∶1253-1258.
    [13]Tsui TY, Lau CK, Ma J, et al.Raav-mediated stable expressionof heme oxygenase-1 in stellates:a new approach to attenuate liverfibrosis in rats[J].Hepatology, 2005, 42 (2) ∶335-42.
    [14]Chen C, Zhang J, Li J, et al.Hydrodynamic-based in vivo trans-fection of retinoic X receptor-alpha gene can enhance vitamin A-induced attenuation of liver fibrosis in mice[J].Internist (Berl) , 2005, 46 (7) ∶731-2, 734-6, 738-40.
    [15]Zhong Z, Froh M, Wheeler MD, et al.Viral gene delivery of su-peroxide dismutase attenuates experimental cholestasis-induced liverfibrosis in the rat[J].Gene Ther, 2002, 9∶183-191.
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  • 出版日期:  2007-05-20
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