非酒精性脂肪性肝炎发病机制的研究进展

裴强; 王晓素; 王宪波

非酒精性脂肪性肝炎发病机制的研究进展

1. 上海中医药大学附属岳阳医院
2. 北京地坛医院

基金项目:

上海市卫生局课题(编号:2004L003A)；

详细信息

中图分类号: R575.1
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出版历程
- 出版日期: 2008-04-20

Research funding:

摘要

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参考文献(15)

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[3]Sanyal AJ, Campbell-Sargent C, Mirshahi F, et al.Nonalcoholicsteatohepatitis:association of insulin resistance and mitochondrial ab-normalities[J].Gastroenterology, 2001, 120 (5) ∶1183-1192.

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[5]Chen NG, Reaven GM.Fatty acid inhibition of glucose-stimulatedinsulin secretion is enhanced in pancreatic islets from insulin-resist-ant rats[J].Metabolism, 1999, 48 (10) ∶1314-1317.

[6]Kim JK, Kim YJ, Fillmore JJ, et al.Prevention of fat-induced in-sulin resistance by salicylate[J].J Clin Invest, 2001, 108 (3) ∶437~446.

[7]Ikegami H, Ogihara T.Genetic susceptibility to diabetes and hyper-tension[J].Nippon Rinsho, 2003, 61 (7) ∶1105-1112.

[8]聂青和, 王全楚.过氧化酶体β氧化与脂肪性肝炎[J].肝脏, 2001, 6∶191.

[9]曾民德.脂肪肝发病机制“二次打击”的假设[J].肝脏, 2001, 9 (3) ∶145.

[10]范建高.重视非酒精性脂肪性肝病发病机制的研究[J].国外医学.消化系疾病分册, 2003, 23 (6) ∶323-326.

[11]曾民德.葡萄糖毒性、脂肪毒性与非酒精性脂肪性肝病[J].中华肝脏病杂志, 2005, 13 (2) ∶81-82.

[12]Watanabe N, Miura S, Zeki S, et al.Hepatoceller oxidativeDNAinjury induced by macrophage-derived nitric oxide[J].FreeRadic Biol Med, 2001, 30 (9) ∶1019-1028.

[13]Sanyal AJ, Campbell-Sargent C, Mirshahi F, et al.Nonalcoholicsteatohepatitis:association of insulin resistance and mitochondrial ab-normalities[J].Gastroenterology, 2001, 120 (5) ∶1183-1192.

[14]Rashid A, Wu TC, Huang CC, et al.Mitochondrial proteins thatregulate apoptosis and necrosis are induced in mouse fatty liver[J].Hepatology, 1999, 29 (4) ∶1131-1138.

[15]Angulo P.Nonalcoholic fatter liver disease[J].N Engl J Med, 2002, 346 (16) ∶1221-1231.

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