3.0T磁共振弥散加权成像对肝硬化的诊断价值初步研究

封海龙; 李彩英; 殷小平; 冯平勇; 崔彩霞; 池琛

3.0T磁共振弥散加权成像对肝硬化的诊断价值初步研究

1. 河北省直属机关第二门诊部放射科
2. 河北医科大学第二医院医学影像科

详细信息

中图分类号: R445.2;R575.2
计量
- 文章访问数: 2319
- HTML全文浏览量: 13
- PDF下载量: 867
- 被引次数: 0
出版历程
- 出版日期: 2009-04-20

摘要

摘要: 目的初步探讨磁共振弥散加权成像ADC值对肝硬化的诊断价值。方法采用3.0T全身磁共振扫描系统对23例肝硬化患者、15例健康志愿者（对照组）行轴位弥散加权成像扫描,b值选用0、500、800、1000 s/mm2,分别在肝脏右前叶、右后叶、左内叶测量各组的ADC值,进行统计学分析。结果两组中肝脏左叶ADC值大于肝脏右叶的ADC值,且具有显著性差异;Z=-4.621P=0.0001;右前叶ADC值略大于右后叶ADC值,两者之间未见显著性差异,Z=-1.552P=0.06。b=500、800、1000 s/mm2时肝硬化组肝脏的ADC值均低于对照组肝脏的ADC值,且与对照组肝脏ADC值之间均有显著性差别。结论3.0T磁共振弥散加权成像ADC值在诊断肝硬化引起弥漫肝实质损害中具有很大的临床价值。
- 磁共振成像 /
- 弥散加权成像 /
- 表观弥散系数 /
- 局灶性病变 /
- 肝硬化 /
- 肝脏
Abstract: Objective To investigate the diagnostic value of apparent diffusion coefficient (ADC) value of diffusion weighted imaging in liver cirrhosis.Methods Diffusion weighted imaging was performed in 23 cirrhotic patients and 15 healthy controls (control group) at 3.0 Tesla magnetic resonance when b value was0、500、800、1000s/mm2.The ADC value in each group was measured and analyzed in right anterior segment, right posterior segment and left medial segment.Results The ADC value measured in left segment was larger than that in right segment.And there was significant difference between them Z=-4.621 P=0.0001) .The ADC value measured in right posterior segment was lower slightly than that in right anterior segment, However, there was no significant difference between them (Z=-1.552 P=0.06) .The ADC value of liver cirrhosis was lower significantly than contractive group when b=500s/mm2, b= 800s /mm2 and b=1000s/mm2, respectively.Conclusion ADC value has an important clinical role on diagnosis of liver diffuse lesions by virtue of cirrhosis at 3.0 Tesla MRI diffusion weighted imaging.
- magnetic resonance imaging (MRI) /
- diffusion weighted imaging (DWI) /
- apparent diffusion coefficient (ADC) /
- focal hepatic lesion /
- liver cirrhosis /
- liver

HTML全文

参考文献(9)

[1]Girometti R, Furlan A, Bazzocchi M, et al.Diffusion-weightedMRI in evaluating liver fibrosis∶a feasibility study in cirrhotic pa-tients[J].Radiol (Torino) , 2007, 112 (3) ∶394-408.

[2]Lewin M, Poujol-Robert A, Bo lle PY, et al.Diffusion-weighted magnetic resonance imaging for the assessment of fibrosisin chronic hepatitis C[J].Hepatology, 2007, 46 (3) ∶658-665.

[3]Hsu FO, Chiou YY, Chen CY, et al.Diffusion-weighted magnet-ic resonance imaging of the liver in hepatitis B patients with Child-Pugh a cirrhosis[J].Kaohsiung J Med Sci, 2007, 23 (9) ∶442-446.

[4]Aube C, Racineux PX, Lebigot J, et al.Diagnosis and quantifica-tion of hepatic fibrosis with diffusion weighted MR imaging∶pre-liminary results[J].J Radiol, 2004, 85 (6 Pt 1) ∶717-719.

[5]Wang K, Wang PJ, Zhao ZH.Functional MRIin chronic liver dis-ease of hepatitis b patients[J].Zhonghua Gan Bing Za Zhi, 2006, 14 (8) ∶590-596.

[6]杨正汉, 谢敬霞, 胡碧芳, 等.肝硬化组织表观扩散系数改变及其可能机制的实验研究[J].中国医学影像技术, 2002, 18 (9) ∶849-851.

[7]Boulanger Y, AmaraM, Lepanto L, et al.Diffusion-weighted MRimaging of the liver of hepatitis C patients[J].NMR Biomed, 2003, 16 (3) ∶132-136.

[8]YoshikawaT, Kawamitsu H, Mitchell DG, et al.ADC measure-ment of abdominal organs and lesions using parallel imaging tech-nique[J].AJR, 2006, 187 (6) ∶1521-1530.

[9]Nasu K, Kuroki Y, Sekiguchi R, et al.Measurement of the appar-ent diffusion coefficient in the liver∶is it a reliable indexfor hepat-ic disease diagnosis?[J].Radiat Med, 2006, 24 (6) ∶438-44.

施引文献

资源附件(0)

访问统计