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The prevalence of fatty liver disease and its relationship with metabolic syndrome
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摘要: 目的了解乌鲁木齐地区机关汉族成人非酒精性脂肪肝及酒精性脂肪肝的流行状况,并分析非酒精性脂肪肝与代谢综合征的关系。方法对1037例体检者的问卷调查、体格检查、生化、肝脏超声检查等相关资料进行分析。结果乌鲁木齐地区成人脂肪肝检出278例,脂肪肝发生率为检出率为26.8%,非酒精性脂肪肝188例,占18.1%,其中男性161例,女性27例;酒精性脂肪肝90例,占8.7%,其中男性84例,女性6例,男性NAFLD高于女性。NAFLD患者合并MS共计115例,伴有率为61.2%。结论乌鲁木齐地区机关汉族成人脂肪肝(NAFLD及AFLD)患病率远高于国内以及世界范围平均患病率,体现了低龄化趋势及中年年龄段的患病高峰特点;年龄、BMI、WHR、TG以及FPG为NAFLD的相关危险因素,NAFLD可以作为MS组成成分之一。Abstract: Objective To determine the prevalence of fatty liver disease and its impact, and evaluate the relationship between non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) .Methods A cross-sectional survey was conducted on 1037 civil servants in Urumuqi using questionnaire and data collected were analyzed.Results The prevalence of fatty liver disease was found to be 26.8%, of which the prevalence of nonalcoholic and alcohol fatty liver diseases were 18.1% and 8.7%, respectively.The percentage of combined MS with NAFLD was 61.2% and was significantly higher than the control group (28.6%) (P<0.005) .Conclusion There is higher prevalence of non-alcoholic and alcoholic fatty liver disease than the previous reports in young and middle age groups.Middle age, BMI, WHR, TG and FPG are the possible risk factors that are closely related to NAFLD.
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Key words:
- fatty liver disease /
- prevalence /
- metabolic syndrome
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