Functional assessment and prognosis of liver disease
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摘要: 肝功能的评估分为静态检验和动态检验。静态检验包括反映合成的白蛋白、胆红素等指标。动态检验包括吲哚菁绿(ICG)清除试验等。吲哚菁绿(ICG)清除试验通常以15min血中ICG滞留率(ICGR15)或ICG清除率(ICGK)作为衡量指标,目前使用光学传感器可以从体外对体内的ICG浓度进行连续检测,省时快捷。CTP评分、MELD评分等是常用预后评价模型,但还需进一步完善。Gc球蛋白,CD163等一些新的指标已显示出一些前景。Abstract: Liver function evaluation includes static and dynamic tests.Albumin, bilirubin and some other biochemical parameters can be used to reflect the degree of liver injury.Recently, indocyanine green retention rate at 15 min (ICG (R15) ) has been considered a sensitive dynamic marker for the liver's reserve function.CTP and MELD score often be used to evaluate the prognosis of end stage liver disease and liver failure, but need to be improved.A few new biomarkers such as Gc-globulin and CD163 have shown some promising prognostic value.
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Key words:
- liver function test /
- indocyanine green /
- prognosis
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