瘦素及脂联素与非酒精性脂肪性肝病

孔银; 张岭漪

瘦素及脂联素与非酒精性脂肪性肝病

孔银,
张岭漪

兰州大学第二医院肝病科甘肃省消化肿瘤重点实验室

详细信息

中图分类号: R575.5
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出版历程
- 出版日期: 2011-04-20

The role of leptin and adiponectin in non-alcoholic fatty liver disease

摘要

摘要: 非酒精性脂肪性肝病(NAFLD)作为代谢综合征在肝脏的表现,是一个多因素共同作用的结果,近年来已成为临床高发疾病之一。除了胰岛素抵抗(IR)在本病发生发展过程中起着重要作用外,脂联素(APN)、瘦素(LP)水平变化与胰岛素抵抗以及与NAFLD的关系受到关注。本文就脂联素(APN)、瘦素(LP)在NAFLD发病中的作用予以综述。
- 瘦素 /
- 脂联素 /
- 脂肪肝
Abstract: Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome.Currently it is one of the highest incidence of disease worldwide, it is considered that the pathogenesis of NAFLD to be a multifactorial process.Insulin resistance (IR) has been confirmed to be implicated in the pathogenesis and progression of NAFLD.Recent studies focused on the role of leptin and adiponectin in NAFLD.We summarized the recent findings concerning the role of leptin and adiponectin in NAFLD.
- leptin /
- adiponectin /
- fatty liver

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参考文献(20)

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