Case-control study of two different embolization agents in the superselective arterial embolization of hepatic hemangiomas
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摘要: 目的探讨平阳霉素碘油乳剂和Embosphere微球两种不同栓塞剂超选择动脉栓塞治疗肝血管瘤的临床疗效。方法 40例肝血管瘤患者随机分成两组行超选择性动脉栓塞治疗,其中A组(20例)采用平阳霉素碘油乳剂作为栓塞剂,B组(20例)采用Embosphere微球作为栓塞剂,比较两组治疗效果。结果所有患者治疗前有临床症状者治疗后缓解或消失。所有患者栓塞治疗后6个月复查肝脏彩超或CT,A组中瘤体缩小15例,稳定5例,无效0例;B组中瘤体缩小16例,稳定4例,无效0例;两组疗效差异没有统计学意义。两组术后均未出现胆囊坏死、胆管狭窄和肝坏死等严重并发症。结论平阳霉素碘油乳剂和Embosphere微球两种栓塞剂超选择性动脉栓塞治疗肝血管瘤均安全有效。Abstract: Objective To assess the clinical efficacy of superselective hepatic arterial embolization with Pingyangmycin lipiodol emulsion or Embosphere particles for patients with hepatic cavernous hemangioma.Methods Forty patients with hepatic cavernous hemangioma were randomly divided into two groups.Twenty cases in group A were treated with superselective arterial embolization with Pingyangmycin lipiodol emulsion, whereas the 20 cases in group B were embolized by Embosphere particles.The efficiency of the two groups were compared and analyzed.Results The clinical symptoms had all deviated or disappeared in all patients after both the treatments.All the cases were performed CT after six months post embolization.In group A, the sizes of hemangiomas were decreased in 15 cases, stabilized in 5 cases and no inefficient case;In group B, the sizes of hemangiomas were decreased in 16 cases, stabilized in 4 cases and no inefficient case.Statistical analysis showed no significant difference between the two groups (P>0.05) .No severe complications such as gallbladder injury, bile duct stricture, and liver failure developed during and after therapy.Conclusion Superselective hepatic arterial embolization with Pingyangmycin lipiodol emulsion or Embosphere particles are effective and safet method for patients with hepatic cavernous hemangioma.a.
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Key words:
- liver neoplasms /
- hemangioma /
- embolization
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