对《丙型肝炎防治指南》中有关“实验室诊断”抗体和核酸检测内容的思考

李金明

对《丙型肝炎防治指南》中有关“实验室诊断”抗体和核酸检测内容的思考

李金明

北京医院卫生部临床检验中心

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中图分类号: R512.63
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出版历程
- 出版日期: 2011-08-20

Advice on the detection of antibody and RNA in the guideline for HCV infection

Li JinMing

摘要

摘要: <正>2004年3月由中华医学会肝病学分会和中华医学会传染病与寄生虫病学分会联合制定发布了《丙型肝炎防治指南》,随着对HCV感染检测研究的进展,人们对有关检验项目的理解更多更深,指南修改在即,现提出几点建议。1抗-HCV抗体的检测机体感染HCV后,可产生针对HCV结构区和非
- 肝炎,丙型 /
- 抗体,病毒 /
- RNA,病毒 /
- 实验室技术和方法
- hepatitis C /
- antibodies /
- viral /
- RNA

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参考文献(16)

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[8]Oethinger M, Mayo DR, Falcone J, et al.Efficiency of the orthoVITROS assay for detection of hepatitis C virus-specific antibodiesincreased by elimination of supplemental testing of samples with verylow sample-to-cutoff ratios[J].J Clin Microbiol, 2005, 43 (5) :2477-2480.

[9]任芙蓉, 龚晓燕, 李京京, 等.献血员丙型肝炎病毒抗体酶免疫法检测试剂的测量值与其真阳性的相关性[J].中华肝脏病杂志, 2005, 13 (4) :255-258.

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[12]张瑞, 李金明.丙型肝炎病毒感染临床检测程序的建立及结果报告与解释[J].中华检验医学杂志, 2010, 33 (10) :990-992.

[13]Saldanha J, Lelie N, Heath A.Establishment of the first interna-tional standard for nucleic acid amplification technology (NAT) as-says for HCV RNA.WHO Collaborative Study Group[J].VoxSang, 1999, 76 (3) :149-158.

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[15]王露楠, 吴健民, 李金明, 等.丙型肝炎病毒核酸检测的国家标准物质的研制[J].中华检验医学杂志, 2006, 29 (4) :354-358.

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