胰性脑病的综合治疗进展

赵佳媛; 王智昊; 吴扬

胰性脑病的综合治疗进展

吉林大学白求恩第一医院急诊科

详细信息

中图分类号: R576
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出版历程
- 出版日期: 2011-11-20

Advances in comprehensive treatment of pancreatic encephalopathy

摘要

摘要: 胰性脑病(PE)是重症急性胰腺炎的严重并发症之一,以脑神经症状为主要表现,虽然此并发症发生率低,但却有较高的病死率。目前,对PE的治疗尚未取得根本性进展,还缺乏特异性方法,仍以综合治疗为主,本文就PE治疗进展作一综述。
- 脑疾病 /
- 代谢性
Abstract: Pancreatic encephalopathy (PE) is one of the serious complications of severe acute pancreatitis, with symptoms of nervous system.Although the incidence rate of complication is low, the mortality is high.At present, there is no fundamental progress, and the comprehensive treatment is still considered as the principal therapy even though lacking specificity.The progress of PE treatment was reviewed in this paper.
- brain disease /
- metabolic

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参考文献(37)

[1]汪谦, 李湘竑.SAP病人胰性脑病的研究进展[J].中国实用外科杂志, 2004, 24 (1) :63-64.

[2]Menva MA, Murraay GB.Pancreatic encephalopathy[J].Biol Psychiatry, 1989, 25 (3) :781-785.

[3]钱祝银, 刘训良.胰性脑病研究进展[J].江苏医药, 1996, 22 (8) :551-552.

[4]王家永.加贝酯治疗急性出血坏死性胰腺炎疗效观察[J].中国医药指南, 2010, 8 (27) :110-111.

[5]莫梅, 张俊文.施他宁和加贝酯治疗急性胰腺炎疗效观察[J].华西医学, 2009, 24 (10) :2571-2573.

[6]李鸿, 羊伟峰.奥美拉唑治疗急性胰腺炎的疗效观察[J].海峡药学, 2010, 22 (12) :186-187.

[7]杨樟卫, 胡晋红, 马凤贤等.奥曲肽治疗急性胰腺炎疗效和经济学的评价[J].中华医院管理杂志, 1999, 15 (2) :81-84.

[8]严伟, 王刚.施他宁在治疗急性胰腺炎的临床应用[J].药学实践杂志, 1999, 17 (4) :212-214.

[9]冯鹏才, 王立俊, 梁俊锋, 等.施他宁和生长激素联用治疗重症急性胰腺炎[J].医师进修杂志, 2000, 23 (2) :38.

[10]余德刚, 蔡庆勇, 钱永琴, 等.胰性脑病的中西医结合治疗[J].现代中西医结合杂志, 2000, 9 (12) :1106-1107.

[11]杨熙平, 王慕新, 谷立文.急性胰腺炎抗胰酶疗法[J].实用外科杂志, 1989, 9 (1) :41-42.

[12]Koizumi R, Kanai H, Maezawa A, et al.Therapeutic effectsof ulinastatin on experimental crescentic glomerulonephritis inrats[J].Nephron, 2000, 84 (4) :347.

[13]唐蕤.乌司他丁与施他宁联合治疗重症急性胰腺炎的临床研究[J].湘南学院学报 (医学版) , 2006, 8 (1) :50-51.

[14]Ayus JC, Arieff AI.Chronic hyponat remic encephalopaghy inpostmenopausal women[J].JAMA, 1999, 281 (24) :2299-2304.

[15]Bansal D, Bhalla A, Bhasin DK, et al.Safety and efficacy ofvitamin-based antioxidant therapy in patients with severe a-cute pancreatitis:A randomized controlled trial[J].Saudi JGastroenterol, 2011, 17 (3) :174-179.

[16]Hegazi R, Raina A, Graham T, et al.Early jejunal feeding initia-tion and clinical outcomes in patients with severe acute pancre-atitis[J].J Parenter Enteral Nutr, 2011, 35 (1) :91-96.

[17]Wall I, Badalov N, Baradarian R, et al.Decreased mortalityin acute pancreatitis related to early aggressive hydration[J].Pancreas, 2011, 40 (4) :547-550.

[18]Tenner S.Fluid resuscitation in severe acute pancreatitis[J].Clin Gastroenterol Hepatol, 2010, 8:16-19.

[19]王艳茹, 麻继臣, 张晓岚.胰性脑病的诊治进展[J].医学综述, 2010, 16 (4) :595-598.

[20]UK Working Party on Acute Pancreatitis.UK guidelines forthe management of acute pancreatitis.Gut, 2005, 54 (Suppl3) :iii1-iii9.

[21]Isenmann R, Rau B, Beger HG.Bacterial infection and ex-tent of necrosis are determinants of organ failure in patients with acute necrotizing pancreatitis[J].Br J Surg, 1999, 86 (8) :1020-1024.

[22]Dellinger EP, Tellado JM, Soto NE, et al.Early antibiotictreatment for severe acute necrotizing pancreatitis:a ran-domized, double-blind, placebo-controlled study.AnnSurg, 2007, 245 (5) :674-683.

[23]Besselink MG, van Santvoort HC, Boermeester MA, et al.Timing and impact of infections in acute pancreatitis[J].Br JSurg, 2009, 96 (3) :267-273.

[24]Otto W, Komorzycki K, Krawczyk M.Efficacy of antibioticpenetration into pancreatic necrosis.HPB (Oxford) , 2006, 8 (1) :43-48.

[25]Drewelow B, Koch K, Otto C, et al.Penetration of ceftazi-dime into human pancreas[J].Infection 1993, 21 (4) :229-234.

[26]Adam U, Herms S, Werner U, et al.The penetration of cip-rofloxacin into human pancreatic and Peripancreatic necrosesin acute necrotizing pancreatitis[J].Infection, 2001, 29 (6) :326-331.

[27]闵东, 汤耀卿, 瞿洪平, 等.抗生素降阶梯治疗急性胰腺炎非手术治疗中的应用[J].中国实用外科杂志, 2003, 23 (9) :526.

[28]De Waele JJ.Rational use of antimicrobials in patients withsevere acute pancreatitis[J].Semin Respir Crit Care Med.2011, 32 (2) :174-180.

[29]Hoerauf A, Mammer S, Muller M, et al.Intraabdominal Candi-da infection during acute necretizing pancreatitis has a highprevalence and is associated with increased mortality[J].CritCare Med, 1998, 26 (12) :2010-2015.

[30]Senn L, Eggimann P, Ksontini R, et al.Caspofungin for pre-vention of intra-abdominal candidiasis in high-risk surgicalpatients[J].Intensive Care Med, 2009, 35 (5) :903-908.

[31]Hershkoviz R, Bruck R, Aeed H, et al.Treatment of con-canavalin A-induced hepatitis in mice with low molecularweight heparin[J].J Hepatol, 1999, 31 (5) :834-840.

[32]邱氟, 吕新生, 李宜雄, 等.低分子量肝素预防重症急性胰腺炎并发胰性脑病的前瞻性临床研究[J].中华肝胆外科杂志, 2006, 12 (9) :622-624.

[33]Nagar AB, Gorelick FS.Acute pancreatitis[J].Curr Op inGastroenterol, 2004, 20:439-443.

[34]Zhou XZ, Mao QS, Chen YQ.Effect of verapamil on the alterat ion of phospholipase A2 activity in acute pancreatitis rats[J].Chinese Journal of General Surgery, 2001, 10 (4) :317-319.

[35]罗爵云, 谭同花, 李鸿雁.纳洛酮加长效托宁治疗急性水肿型胰腺炎的疗效观察[J].中国现代医学杂志, 2001, 11 (2) :64-65.

[36]Wan MH, Li J, Gong HL, et al.Clinical observation on theeffect of dexamethasone and Chinese herbal decoction forpurgation in severe acute pancreatitis patients[J].Chin J In-tegr Med, 2011, 17 (2) :141-145.

[37]张德重.急性重症胰腺炎的外科治疗体会[J].中国社区医师[J].医学专业, 2011, 13 (1) :38.

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