替比夫定治疗慢性乙型肝炎的研究进展

王海燕; 王煜; 彭晓明; 刘娅

替比夫定治疗慢性乙型肝炎的研究进展

1. 宁夏医科大学
2. 宁夏医科大学总医院感染疾病科

基金项目:

宁夏自然科学基金(NZ10118)；

详细信息

中图分类号: R512.62
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出版历程
- 出版日期: 2011-12-20

Recent advancement of telbivudine in the treatment of chronic hepatitis B

Research funding:

摘要

摘要: 替比夫定是一种新型的抗HBV作用的核苷类似物,其HBeAg血清学转换率高、起效早,耐药发生率低。了解替比夫定的药理作用,选择合适的病例进行治疗,在治疗过程中及时监测,根据第24周时患者的HBV DNA水平来指导后期的治疗,有助于达到长期抑制HBV的目的。
- 肝炎,乙型,慢性 /
- 肝炎病毒,乙型 /
- 替比夫定
Abstract: Telbivudine is a novel nucleoside analogue against hepatitis B virus with fast HBeAg seroconversion rate, early viral response and low drug tolerance rate.It is helpful in achieving the long term suppression of HBV by understanding the pharmacokinetics of Telbivudine, selecting the appropriate patients for treatment, timely monitoring the patients during treatment and guiding post-treatment by the patient's first 24 weeks HBV-DNA levels.
- hepatitis B /
- chronic /
- hepatitis B virus

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参考文献(21)

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