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Effects of marine in the treatment of chronic hepatitis B patients with low viral load
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摘要: 目的观察序贯应用苦参素胶囊和苦参素注射液治疗低病毒载量慢性乙型肝炎的疗效。方法选择60例低病毒载量慢性乙型肝炎患者,随机分为对照组和治疗组各30例,对照组给予常规保肝治疗,治疗组同时序贯应用苦参素胶囊和苦参素注射液治疗,总疗程24周,观察两组治疗4、12、24周时的ALT、HBV DNA转阴率及HBeAg/抗-HBe血清转换率。结果治疗组在改善肝功能、HBV DNA转阴率及HBeAg/抗-HBe血清转换率方面优于对照组。结论序贯应用苦参素胶囊和苦参素注射液治疗低病毒载量慢性乙型肝炎患者可以获得较高的应答率。Abstract: Objective To observe the effects of Marine in chronic hepatitis B patients with low viral load.Methods Sixty patients with CHB were randomly divided into control group and treatment group.Patients in the control group received general liver protection therapy, while those in the treatment group received marine capsules and marine injection sequentially.The period of treatment was 24 weeks.The ALT, HBV DNA and HBeAg/HBeAb were checked 4 weeks, 12 weeks and 24 weeks after treatment.Results At the end of treatment the negative conversion rates of ALT and HBV DNA and HBeAg/HBeAb seroconversion rate were significantly higher in the treatment group than in the control group. Conclusion Marine capsules and marine injection sequentially in the treatment of chronic hepatitis B patients with low viral load can obtain higher rate of virological response and serological response.
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Key words:
- marine /
- hepatitis B /
- chronic
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