乙型肝炎病毒感染的流行现状

胡晓丽; 赵宏伟; 吴晓岩; 牛俊奇

乙型肝炎病毒感染的流行现状

1. 吉林大学第一医院肝胆胰内科
2. 黑龙江省医院感染内科
3. 黑龙江省医院实验诊断部

详细信息

中图分类号: R512.62
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出版历程
- 出版日期: 2012-06-20

Prevalence of hepatitis B virus infection

摘要

摘要: <正>乙型肝炎病毒(HBV)感染是一个重要的公共卫生问题,据世界卫生组织(WHO)公布的数据,全球20亿人已感染HBV,其中3.5～4亿人为慢性HBV携带者[1]。HBV感染可以引起急性和慢性肝脏疾病,包括肝硬化和肝癌[1]。乙型肝炎引起的与HBV相关的肝衰竭、肝硬化、肝癌,每年会导致100万人死亡。中国是HBV感染的高发区,2006年进行的HBV感染的血清流行病学调查结果显示,HBsAg携带率为总人口的7.18%。因此,
- 肝炎病毒,乙型 /
- 流行病学因素
- hepatitis B virus /
- epidemiologic factors

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参考文献(49)

[1]Poynard T, Yuen MF, Ratziu V, et al.Viral hepatitis C[J].Lan-cet, 2003, 362:2095-2100.

[2]Liang X, Bi S, Yang W, et al.Epidemiological serosurvey of hepatitis B in China--declining HBV prevalence due to hepatitis B vaccination[J].Vaccine, 2009, 27 (47) :6550-6557.

[3]Zhang H, Li Q, Sun J, et al.Seroprevalence and risk factors for hepatitis B infection in an adult population in Northeast China[J].Int J Med Sci, 2011, 8 (4) :321-331.

[4] Okamoto H, Tsuda F, Sakugawa H, et al.Typing hepatitis B virus by homology in nucleotide sequence:comparison of surface antigen subtypes[J].J Gen Virol, 1988, 69 (Pt10) :2575-2583.

[5]Stuyver L, De Gendt S, Van Geyt C, et al.A new genotype of hep-atitis B virus:complete genome and phylogenetic relatedness[J].J Gen Virol, 2000, 81 (Pt1) :67-74.

[6]Magnius LO, Norder H.Subtypes, genotypes and molecular epide-miology of the hepatitis B virus as reflected by sequence variability of the S-gene[J].Intervirology, 1995, 38 (1-2) :24-34.

[7] Norder H, Courouce AM, Magnius LO.Complete genomes, phylo-genetic relatedness, and structural proteins of six strains of the hepa-titis B virus, four of which represent two new genotypes[J].Virolo-gy, 1994, 198 (2) :489-503.

[8]Takahashi K, Akahane Y, Hino K, et al.Hepatitis B virus genomic sequence in the circulation of hepatocellular carcinoma patients:comparative analysis of40full-length isolates[J].Arch Virol, 1998, 143 (12) :2313-2326.

[9]Arauz-Ruiz P, Norder H, Robertson BH, et al.Genotype H:a new Amerindian genotype of hepatitis B virus revealed in Central America[J].J Gen Virol, 2002, 83 (Pt8) :2059-2073.

[10]Zeng G, Wang Z, Wen S, et al.Geographic distribution, virologic and clinical characteristics of hepatitis B virus genotypes in China[J].J Viral Hepat, 2005, 12 (16) :609-617.

[11]Kao JH, Chen PJ, Lai MY, et al.Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B[J].Gas-troenterology, 2000, 118 (3) :554-559.

[12]Kobayashi M, Arase Y, Ikeda K, et al.Clinical characteristics of patients infected with hepatitis B virus genotypes A, B, and C[J].J Gastroenterol, 2002.37 (1) :35-39.

[13]Ding X, Mizokami M, Yao G, et al.Hepatitis B virus genotype dis-tribution among chronic hepatitis B virus carriers in Shanghai, China[J].Intervirology, 2001, 44 (1) :43-47.

[14]Thakur V, Guptan RC, Kazim SN, et al.Profile, spectrum and significance of HBV genotypes in chronic liver disease patients in the Indian subcontinent[J].J Gastroenterol Hepatol, 2002, 17 (2) :165-170.

[15]Devarbhavi HC, Cohen AJ, Patel R, et al.Preliminary results:outcome of liver transplantation for hepatitis B virus varies by hepa-titis B virus genotype[J].Liver Transpl, 2002, 8 (6) :550-555.

[16]Zollner B, Petersen J, Schroter M, et al.20-fold increase in risk of lamivudine resistance in hepatitis B virus subtype adw[J].Lan-cet, 2001, 357 (9260) :934-935.

[17]Norder H, Courouce AM, Coursaget P, et al.Genetic diversity of hepatitis B virus strains derived worldwide:genotypes, subgeno-types, and HBsAg subtypes[J].Intervirology, 2004, 47 (6) :289-309.

[18]许军, 王齐欣, 范春蕾, 等.中国南北两城市乙型肝炎病毒基因型与血清型的构成差异[J].中华实验和临床病毒学杂志, 2003, 17 (4) :327-329.

[19]Gutierrez-Garcia ML, Fernandez-Rodriguez CM, Lledo-Navarro JL, et al.Prevalence of occult hepatitis B virus infection[J].World J Gastroenterol, 2011, 17 (2) :1538-1542.

[20]Fang Y, Shang QL, Liu JY, et al.Prevalence of occult hepatitis B virus infection among hepatopathy patients and healthy people in China[J].J Infect, 2009, 58 (5) :383-388.

[21]Hollinger FB.Hepatitis B virus infection and transfusion medicine:science and the occult[J].Transfusion, 2008, 48 (5) :1001-1026.

[22]Linauts S, Saldanha J, Strong DM.PRISM hepatitis B surface anti-gen detection of hepatits B virus minipool nucleic acid testing yield samples[J].Transfusion, 2008, 48 (7) :1376-1382.

[23]Hourfar MK, Jork C, Schottstedt V, et al.Experience of German Red Cross blood donor services with nucleic acid testing:results of screening more than30million blood donations for human immunodeficiency virus-1, hepatitis C virus, and hepatitis B virus[J].Transfusion, 2008, 48 (8) :1558-1566.

[24]Hui CK, Sun J, Au WY, et al.Occult hepatitis B virus infection in hematopoietic stem cell donors in a hepatitis B virus endemic area[J].J Hepatol, 2005, 42 (6) :813-819.

[25]Guan R, Lui HF.Treatment of hepatitis B in decompensated liver cirrhosis[J].Int J Hepatol, 2011, 2011:918017.[Epub2011Jun23]

[26]Proceedings of the European Association for the Study of the Liver (EASL) International Consensus Conference on Hepatitis B.Sep-tember14-16, 2002.Geneva, Switzerland[J].J Hepatol, 2003, 39 (Suppl1) :S1-235.

[27]Liaw YF, Leung N, Kao JH, et al.Asian-Pacific consensus state-ment on the management of chronic hepatitis B:a2008update[J].Hepatol Int, 2008, 2 (3) :263-283.

[28]Parkin DM, Bray F, Ferlay J, et al.Global cancer statistics, 2002[J].CA Cancer J Clin, 2005, 55:74-108.

[29]Raza SA, Clifford GM, Franceschi S.Worldwide variation in the relative importance of hepatitis B and hepatitis C viruses in hepato-cellular carcinoma:a systematic review[J].Br J Cancer, 2007, 96 (7) :1127-34.

[30]Bertuccio P, Chatenoud L, Levi F, et al.Recent patterns in gastric cancer:a global overview[J].Int J Cancer, 2009, 125 (3) :666-673.

[31] Liang X, Bi S, Yang W, et al.Evaluation of the impact of hepatitis B vaccination among children born during1992-2005in China[J].J Infect Dis, 2009, 200 (1) :39-47.

[32]Helcl J, CástkováJ, Benes C, et al.Control of occupational hepa-titisB among health care workers in the Czech Republic;1982to 1995[J].Infect Control HosP EPid emiol, 2000, 21 (5) :343-346.

[33]Denes AE, Smith JL, Maynard JE, et al.Hepatitis B infection in physicians.Results of a nationwide seroepidemiologic survey[J].JAMA, 1978, 239 (3) :210-212.

[34]Kosgeroglu N, Ayranci U, Vardareli E, et al.Occupational expo-sure to hepatitis infection among Turkish nurses:frequency of nee-dle exposure, sharps injuries and vaccination[J].Epidemiol In-fect, 2004, 132 (1) :27-33.

[35]Todd CS, Nasir A, Stanekzai MR, et al.HIV, hepatitis B, and hepatitis C prevalence and associated risk behaviors among female sex workers in three Afghan cities[J].AIDS, 2010, 24 (Suppl2) :S69-75.

[36]Pinarbasi B, Onel D, Cosan F, et al.Prevalence and virological features of occult hepatitis B virus infection in female sex workers who work uncontrolled in Turkey[J].Liver Int, 2009, 29 (2) :227-230.

[37]Gutierrez M, Tajada P, Alvarez A, et al.Prevalence of HIV-1 non-B subtypes, syphilis, HTLV, and hepatitis B and C viruses among immigrant sex workers in Madrid, Spain[J].J Med Virol, 2004, 74 (4) :521-527.

[38]Camejo MI, Mata G, Díaz M.Prevalence of hepatitis B, hepatitis C and syphilis in female sex workers in Venezuela[J].Rev Saude Publi-ca, 2003, 37 (3) :339-344.

[39]Mak R, Traen A, Claeyssens M, et al.Hepatitis B vaccination for sex workers:do outreach programmes perform better?[J].Sex Transm Infect, 2003, 79 (2) :157-159.

[40]Ishi K, Suzuku F, Saito A, et al.Prevalence of human immunodefi-ciency virus, hepatitis B and hepatitis C virus antibodies and hepatitis B antigen among commercial sex workers in Japan[J].Infect Dis Ob-stet Gynecol, 2001, 9 (4) :215-219.

[41]Forbi JC, Onyemauwa N, Gyar SD, et al.High prevalence of hepa-titis B virus among female sex workers in Nigeria[J].Rev Inst Med Trop Sao Paulo, 2008, 50 (4) :219-221.

[42]Sandesh K, Varghese T, Harikumar R, et al.Prevalence of Hepatitis B and C in the normal population and high risk groups in north Kerala[J].Trop Gastroenterol, 2006, 27:80-83.

[43]Ruan Y, Luo F, Jia Y, et al.Risk factors for syphilis and preva-lence of HIV, hepatitis B and C among men who have sex with men in Beijing, China:implications for HIV prevention[J].AIDS Be-hav, 2009, 13 (4) :663-670.

[44]Sa-Nguanmoo P, Tangkijvanich P, Thawornsuk N, et al.Molecu-lar epidemiological study of hepatitis B virus among migrant workers from Cambodia, Laos, and Myanmar to Thailand[J].J Med Virol, 2010, 82 (8) :1341-1349.

[45]Liu Z, Hou J.Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Dual Infection[J].Int J Med Sci, 2006, 3 (2) :57-62.

[46]Irshad M, Peter S.Spectrum of viral hepatitis in thalassemic chil-dren receiving multiple blood transfusions[J].Indian J Gastroen-terol, 2002, 21 (5) :183-184.

[47]Soriano V, Puoti M, Peters M, et al.Care of HIV patients with chronic hepatitis B:updated recommendations from the HIV-Hep-atitis B Virus International Panel[J].AIDS, 2008, 22 (12) :1399-1410.

[48]Tounkara A, Sarro YS, Kristensen S, et al.Seroprevalence of HIV/HBV coinfection in Malian blood donors[J].J Int Assoc Physicians AIDS Care (Chic) , 2009, 8 (1) :47-51.

[49]Nyirenda M, Beadsworth MB, Stephany P, et al.Prevalence of infec-tion with hepatitis B and C virus and coinfection with HIV in medical inpatients in Malawi[J].J Infect, 2008, 57 (1) :72-77.

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