肝硬化患者脾肝体积比与食管胃底静脉曲张的关系

曾文勇; 蒋鸥; 刘宇; 吴文建

肝硬化患者脾肝体积比与食管胃底静脉曲张的关系

内江市第二人民医院肿瘤中心

基金项目:

四川省卫生厅课题(080225)；

详细信息

中图分类号: R575.2
计量
- 文章访问数: 2227
- HTML全文浏览量: 29
- PDF下载量: 591
- 被引次数: 0
出版历程
- 出版日期: 2012-07-20

Correlation between spleen-liver volume ratio and esophageal and gastric varices in liver cirrhosis patients

Research funding:

摘要

摘要: 目的探讨脾肝体积比在预测静脉曲张程度中的价值。方法对51例确诊的肝硬化患者进行胃镜和增强CT检查,将食管胃底静脉曲张程度分级并计算患者的脾肝体积比;比较这两个指标的相关性和各级静脉曲张患者的脾肝体积比。结果食管胃底静脉曲张的分级与脾肝体积比相关性明显(t=0.693,P<0.001)。各级食管胃底静脉曲张之间的脾肝体积比差异均有统计学意义。结论肝硬化患者随着脾肝体积比值的升高,静脉曲张程度加重,脾肝体积比可以作为无创性检测手段判断静脉曲张程度,为进一步的工作打下了一定的基础。
- 脾肝体积比 /
- 肝硬化 /
- 食管和胃静脉曲张
Abstract: Objective To determine the value of spleen-liver volume ratio as a non-invasive predictive measure of the degree of esophageal and gastric varices.Methods Fifty-one cirrhosis patients underwent endoscopy for grading of esophageal varices (4 grades: 0-3) and enhanced computed tomography to calculate the spleen-liver volume ratio.The Child-Pugh score was calculated to determine the liver disease severity.Analysis of variance was used to investigate the relation between spleen-liver volume ratio and grades of varicose veins and disease severity.Results There was a significant correlation between the degree of esophageal varices and the spleen-liver volume ratio (t=0.693, P<0.001) .However, there was no significant correlation between the Child-Pugh classification and spleen-liver volume ratio (t=0.236, P>0.05) .Conclusion The non-invasive measure of spleen-liver volume ratio is indicative of esophageal and gastric varices severity, with the spleen-liver volume ratio increasing in parallel to increases in grades of esophageal varicose veins.
- spleen-liver volume ratio /
- liver cirrhosis /
- esophageal and gastric varices

HTML全文

参考文献(11)

[1]Heymsfield SB, Fulenwider T, Nordinger B, et al.Accuratemeasurement of liver, kidney and spleen volume and massby computerized axial tomogruphy[J].Ann Intern Med, 1979, 90 (2) :185-187.

[2]GARCIA-Tsao G, Sanyal AJ, Grace ND, et al.Prevention andmanagement of gastroesophageal varices and variceal hemor-rhage in cirrhosis[J].Hepatology, 2007, 46 (3) :922-938.

[3]蒋鸥, 刘宇, 吴文建, 等.脾与残肝体积比在肝癌外科中的应用[J].中国普外基础与临床杂志, 2005, 1 (2) :162-166.

[4]Nevens F, Bustami R, Scheys I, et al.Variceal pressure is afactor predicting the risk of a first variceal bleeding:a pro-spective cohort study in cirrhotic patients[J].Hepatology, 1998, 27 (1) :15-19.

[5]Ogasawara K, Une Y, Nakajima Y, et al.The significance ofmeasurring liver volume using computed tomographic imagesbefore and after hepatectomy[J].Surg Today, 1995, 25 (1) :43-48.

[6]Shirabe K, Shimada M, Gion T, et al.Postoperative liver fail-ure after major hepatic resection for hepatoeefiular carcinomathe modern era with special reference to remnant liver vol-ume[J].J Am Coil Surg, 1999, 188 (3) :304-309.

[7]Groshar D, Slobodin G, Zuckerman E.Quantitation of liverand spleen uptake of (99m) Tc-phytate colloid usingSPECT:detection of liver cirrhosis[J].J Nucl Med, 2002, 43 (3) :312-317.

[8]Zhang XJ, Kan amatsu M, Zhou XR, et al.Differentiation ofcirrhosis by using 3D hepatic volume ratio of LTM in multi-detector row CTscans and MR imaging[J].InternationalCongress Series, 2005, 1281:1163-1168.

[9]Yamaguchi S, Kawanaka H, Yoshida D, et al.Splenic hemo-dynamics and decreased endothelial nitric oxide synthase inthe spleen of rats with liver cirrhosis[J].Life Sci, 2007, 80 (22) :2036-2044.

[10]John CH, Felix WW, David LL, et al.A novel, simple meth-od of functional spleen volume caculation by liver-spleenscan[J].J Nucl Med, 1999, 40 (10) :1745-1755.

[11]涂蓉, 张阳德, 伍保忠, 等.CT肝硬化定量诊断的临床研究[J].临床肝胆病杂志, 2004, 20 (1) :28-29.

施引文献

资源附件(0)

访问统计