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Clinical studies of stem cell transplantation to treat liver cirrhosis
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摘要:
<正>肝硬化是消化系统最常见的一种慢性疾病,是由病毒(HBV、HCV)、酒精等一种或多种原因引起的肝细胞广泛变性、坏死,肝脏弥漫性纤维化病变,进而形成再生结节和假小叶,导致正常肝小叶结构破坏,进一步发展为肝硬化,从而出现腹水、消化道出血、肝性脑病等一系列严重并发症,危及患者生命。目前,我国肝病患者大约7000万人,每年约有100多万人发展为肝硬化,数十万人死于肝硬化。原位肝移植是治疗肝硬化患者最理想的治疗选择,但因供体紧缺、免疫排斥、费用高等原因,导致临床应用十分有限,很难成为常规的治疗手段。随
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