白细胞介素17在器官移植排斥中的作用及机制

秦建杰; 吕凌

白细胞介素17在器官移植排斥中的作用及机制

秦建杰,
吕凌

南京医科大学第一附属医院肝脏移植中心

基金项目:

国家自然科学基金项目(81100270,81070380,811010016)；江苏省国际合作项目(BZ2011041,BZ2012058)；江苏省六大人才高峰项目(ZX05 200904,WS2011106)；

详细信息

中图分类号: R392.4
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出版历程
- 出版日期: 2012-11-20

The role and molecular mechanism of interleukin-17 in organ transplant rejection

Research funding:

摘要

摘要:
<正>器官移植已成为治疗脏器功能衰竭的有效手段,但术后的移植排斥仍然是影响移植物和患者存活的主要问题。同种异体排斥反应的细胞学机制主要为T细胞介导的免疫反应。该群T细胞包括CD4+T和CD8+T细胞,其中尤以CD4+T细胞在移植排斥反应中的作用更为重要。先前研究认为Th1与排斥反应细胞免疫有关;而Th2细胞与体液免疫有关,有保护作用[1]。然而,最近认为Th1、Th2细胞均参与了器官移植排斥
- 白细胞介素17 /
- 器官移植 /
- 移植物排斥
- interleukin-17 /
- organ transplantation /
- graft rejection

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参考文献(25)

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