腹腔镜胆囊切除术切割时间与碳氧血红蛋白含量的关系

章琪; 张清河; 张从雨

腹腔镜胆囊切除术切割时间与碳氧血红蛋白含量的关系

安徽医科大学附属安庆医院普外科

基金项目:

安徽省教育厅自然科学研究项目(项目编号KJ2010B382)；

详细信息

中图分类号: R657.4
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出版历程
- 出版日期: 2013-06-20

Relationship between laparoscopic cholecystectomy operative time and carbonyl hemoglobin content

Department of General Surgery, Anqing Hospital Affiliated to Anhui Medical University

Research funding:

摘要

摘要:
目的探讨腹腔镜胆囊切除手术中切割时间与外周静脉血碳氧血红蛋白(COHb)含量的关系。方法选择腹腔胆囊切除术患者40例,分别于手术切割开始及结束时抽取患者外周静脉血测定COHb含量,对比其前后变化、分析其与切割时间变化的关系。结果腹腔镜手术完成38例,2例患者中转开腹。患者外周静脉血COHb含量术后(11.07%±1.18%)较术前(1.44%±0.26%)明显升高(P<0.05),且在一定时间内与手术切割时间呈正相关(r=0.85)。结论腹腔镜胆囊切除手术中产生的CO可导致外周静脉血COHb含量升高,且手术切割时间越长,COHb含量升高越明显。
- 胆囊切除术,腹腔镜 /
- 一氧化碳 /
- 碳氧血红蛋白
Abstract:
Objective To investigate whether operative time of laparoscopic cholecystectomy impacts the carbonyl hemoglobin (COHb) concentration in peripheral blood.Methods Forty patients with gallstones and indications for laparoscopic cholecystectomy were enrolled in the study.Peripheral venous blood samples were collected at the beginning and end of the operative procedure.COHb concentration was measured by UV spectroscopy.The significance of changes in COHb concentration in relation to time of the operative procedure (rounded to the nearest minute) was assessed by statistical correlation coefficient test.Results The laparoscopic procedure was completed in 38 cases, and two patients required conversion to laparotomy.The content of COHb in peripheral venous blood had significantly increased during the laparoscopic operation (operation beginning: 11.07%±1.18% vs.operation end: 1.44%±0.26%, P<0.05) .The change was positively correlated with operation time (r=0.85) .Conclusion Carbon monoxide produced during the laparoscopic cholecystectomy procedure can lead to an increase in peripheral venous blood COHb.The longer the operation lasts, the greater the increase in COHb.
- cholecystetomy /
- laparoscopic /
- carbon monoxide

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参考文献(11)

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