特发性成人肝内胆管缺失症合并药物性肝损害1例报告

田洲; 李丽; 鲍旭丽; 闾军

特发性成人肝内胆管缺失症合并药物性肝损害1例报告

首都医科大学附属北京佑安医院肝病与肿瘤生物治疗科

基金项目:

北京市卫生系统高层次卫生技术人才培养项目资助(2011-J.L.)；首都医学发展科研基金(2009-3156)；

详细信息

中图分类号: R575
计量
- 文章访问数: 2993
- HTML全文浏览量: 11
- PDF下载量: 654
- 被引次数: 0
出版历程
- 出版日期: 2013-06-20

A case of idiopathic adulthood ductopenia with drug-induced liver damage

Department of Hepatopathy and Cancer Biotherapy, Beijing You′an Hospital Affiliated to Capital Medical University

Research funding:

摘要

摘要:
<正>特发性成人肝内胆管缺失症（idiopathic adulthood ductope-nia,IAD）,是一种病因不明的慢性胆汁淤积性肝病,以成人发病,肝小叶间胆管缺失为主要特征[1-2]。现报道1例因药物性肝损害加重病情从而发现原发疾病为IAD的患者。1病例介绍患者,女,60岁,因"间断恶心、呕吐、尿黄、乏力3年,加重1个月"于2012年3月来我院就诊。3年前无诱因出现恶心、
- 胆管疾病 /
- 胆汁淤积 /
- 肝,中毒性
- bile duct diseases /
- cholestasis /
- hepatitis

HTML全文

参考文献(13)

[1]Ludwig J.Idiopathic adulthood ductopenia:an update[J].MayoClin Proc, 1998, 73 (3) :285-291.

[2]Ludwig J, Wiesner RH, LaRusso NF.Idiopathic adulthood duc-topenia.A cause of chronic cholestatic liver disease and biliary cir-rhosis[J].J Hepatol, 1988, 7 (2) :193-199.

[3]Zhang WS, Wang BE, Jia JD.Idiopathic adult intrahepatic bile ductdeficiency[J].Chin Hepatol, 2004, 9 (4) :264-266. (in Chinese) 张文胜, 王宝恩, 贾继东.特发性成人肝内胆管缺失症[J].肝脏, 2004, 9 (4) :264-266.

[4]Reily CA.Familial intrahepatic cholestatic syndromes[J].SeminLiver Dis, 1987, 7 (2) :119-133.

[5]Bruguera M, Llach J, Rodès J.Nonsyndromic paucity of intrahepat-ic bile ducts in infancy and idiopathic ductopenia in adulthood:thesame syndrome?[J].Hepatology, 1992, 15 (5) :830-834.

[6]Burak KW, Pearson DC, Swain MG, et al.Familial idiopathic a-dulthood ductopenia:a report of five cases in three generations[J].J Hepatol, 2000, 32 (1) :159-163.

[7]Chia SC, Bergasa NV, Kleiner DE, et al.Pruritis as a presentingsymptom of chronic hepatitis C[J].Dig Dis Sci, 1998, 43 (10) :2177-2183.

[8]Dural AT, Genta RM, Goodman ZD, et al.Idiopathic adulthoodductopenia associated with hepatitis C virus[J].Dig Dis Sci, 2002, 47 (7) :1625-1626.

[9]Khanlou H, Sass D, Rothstein K, et al.Idiopathic adulthood duc-topenia:case report and review of the literature[J].Arch InternMed, 2000, 160 (7) :1033-1036.

[10]Moreno A, Carreo V, Cano A, et al.Idiopathic biliary ductopeniain adults without symptoms of liver disease[J].N Engl J Med, 1997, 336 (12) :835-838.

[11]Hartmann H, Grne HJ.Idiopathic ductopenia of adulthood:favor-able effect of ursodeoxycholic acid therapy[J].Z Gastroenterol, 1993, 31 (Suppl 2) :131-133.

[12]Zhang WS, Wang BE, Jia JD, et al.Idiopathic adulthood ductopenia:report of one case[J].Chin J Hepatol, 2005, 13 (9) :714-712. (inChinese) 张文胜, 王宝恩, 贾继东, 等.特发性成人肝内胆管缺失症1例报道[J].中华肝脏病杂志, 2005, 13 (9) :714-717.

[13]Park BC, Park SM, Choi EY, et al.A case of idiopathic adulthoodductopenia[J].Korean J Intern Med, 2009, 24 (3) :270-273.

施引文献

资源附件(0)

访问统计