原发性胆汁性胆管炎合并脂质代谢异常的研究进展

袁诗雨; 杨焕焕; 唐映梅

doi:10.12449/JCH240125

原发性胆汁性胆管炎合并脂质代谢异常的研究进展

DOI: 10.12449/JCH240125

昆明医科大学第二附属医院消化内科，昆明 650101

基金项目:

云南省医学领军人才项目 (L-2019013);

云南万人项目 (YNWR-MY-2018-028);

昆明医科大学第二附属医院临床研究项目 (2020ynlc010)

利益冲突声明：本文不存在任何利益冲突。

作者贡献声明：袁诗雨负责起草文章，对行文的思路和设计有关键贡献；杨焕焕、唐映梅参与了修改文章关键内容。

详细信息

通信作者:
唐映梅， tangyingmei_med@kmmu.edu.cn （ORCID： 0000-0002-0731-4198）

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出版历程
- 收稿日期: 2023-05-04
- 录用日期: 2023-05-26
- 出版日期: 2024-01-23

Research advances in primary biliary cholangitis with dyslipidemia

Department of Gastroenterology，The Second Affiliated Hospital of Kunming Medical University，Kunming 650101，China

Research funding:

Medicine Leading Talents of Yunnan Province (L-2019013);

Yunnan Wanren Project (YNWR-MY-2018-028);

Clinical Research Project of the Second Affiliated Hospital of Kunming Medical University (2020ynlc010)

More Information

Corresponding author: TANG Yingmei， tangyingmei_med@kmmu.edu.cn （ORCID：0000-0002-0731-4198）

摘要

摘要: 原发性胆汁性胆管炎（PBC）是一种以肝内中小胆管进行性、非化脓性炎症为特征的自身免疫性肝病。近期研究发现PBC患者中脂质代谢异常较为常见，76%的PBC患者常合并血脂异常，其作用及危害备受关注。脂质代谢紊乱在PBC发展中起重要作用，本文主要从脂质代谢紊乱在PBC中的表现及作用、诊断及治疗方面的研究进展展开综述，以期为PBC治疗提供新的思路。
- 原发性胆汁性胆管炎 /
- 脂代谢障碍 /
- 炎症
Abstract: Primary biliary cholangitis （PBC） is an autoimmune liver disease characterized by progressive and non-purulent inflammation of small- and medium-sized bile ducts in the liver. Recent studies have shown that abnormal lipid metabolism is relatively common in patients with PBC， and 76% of PBC patients have dyslipidemia. The effects and harms of dyslipidemia have attracted much attention. Lipid metabolism disorders play an important role in the progression of PBC. This article mainly reviews the research advances in the manifestation， role， diagnosis， and treatment of lipid metabolism disorders in PBC， so as to provide new ideas for the treatment of PBC.
- Primary Biliary Cholangitis /
- Lipid Metabolism Disorders /
- Inflammation

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参考文献(45)

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