Risk factors, diagnostic criteria, and drug discontinuation criteria for drug- induced liver injury
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摘要: 药物性肝损害是指药物本身或其代谢产物引起的肝损害,是引起肝衰竭的重要原因之一。目前还缺乏有效的预测指标及诊疗手段。从易感因素、诊断和评价标准等方面对药物性肝损害进行介绍。了解药物性肝损害的最新进展,有利于及时发现药物性肝损害的易感患者;合理运用各种评价标准,有助于药物性肝损害的规范化诊疗。Abstract: Drug- induced liver injury ( DILI) is the liver injury caused by drugs or their metabolites, which is the common cause of live failure. Currently, there is still a lack of effective predictors and diagnostic and therapeutic methods for DILI. To gives an introduction to DILI from the aspects of risk factors, diagnostic criteria, causality assessment, etc. To understand the latest research progress in DILI can make for timely identification of patients susceptible to DILI; proper use of causality assessment can help standardize the diagnosis and treatment of DILI.
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Key words:
- hepatitis, toxic /
- risk factors /
- diagnostic
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