肝硬化常见并发症的中医外治法研究进展

施维群; 杨育林; 陆增生; 何创

doi:10.3969/j.issn.1001-5256.2014.04.004

肝硬化常见并发症的中医外治法研究进展

DOI: 10.3969/j.issn.1001-5256.2014.04.004

浙江中医药大学附属第二医院肝病中心

详细信息

中图分类号: R575.2
计量
- 文章访问数: 4184
- HTML全文浏览量: 24
- PDF下载量: 888
- 被引次数: 0
出版历程
- 收稿日期: 2013-12-04
- 出版日期: 2014-04-20

Research advances in external therapy of traditional Chinese medicine for common complications of liver cirrhosis

Liver Center, The Second Affiliated Hospital of Zhejiang Chinese Medical University

摘要

摘要:
门静脉高压、内毒素血症、肝性脑病、腹水为肝硬化常见的并发症,现代医学行之有效的方法不多。介绍了穴位敷贴、中药灌肠、穴位注射、肝病治疗仪肝区照射等常见中医外治法的概念、方法及用途。从肝硬化门静脉高压症、肝硬化内毒素血症、肝硬化肝性脑病、肝硬化腹水甚至乙型肝炎肝硬化抗病毒治疗应答情况等角度回顾近年来穴位敷贴、中药灌肠、穴位注射、肝病治疗仪肝区照射在各自领域的疗效、机制研究等方面的相关文献,肯定了中医外治法对肝硬化并发症治疗的积极作用和疗效,其简便易行、安全性好、价格低廉,患者易于接受。同时,对目前中药外治如何使用透皮促进剂来提高药物吸收度问题、对中医外治法的研究对照组设置等提出进一步研究的建议。
- 肝硬化 /
- 高血压,门静脉 /
- 内毒素血症 /
- 肝性脑病 /
- 腹水 /
- 中医疗法 /
- 综述
Abstract:
Portal hypertension, endotoxemia, hepatic encephalopathy, and ascites are common complications of liver cirrhosis, and there are few effective treatment methods for them in modern medicine.Common concepts, methods, and application of external therapy of traditional Chinese medicine (TCM) , such as acupoint application, TCM enema, acupoint injection, and irradiation of the liver region using liver disease therapy instrument, are introduced.The literature on the efficacy and mechanism of acupoint application, TCM enema, acupoint injection, and irradiation of the liver region using liver disease therapy instrument is reviewed from the aspects of portal hypertension, endotoxemia, hepatic encephalopathy, and ascites in patients with liver cirrhosis and even response to antiviral therapy for hepatitis B cirrhosis.It is concluded that external therapy of TCM is effective, easy to operate, safe, and inexpensive in the treatment of the complications of liver cirrhosis, with easy acceptance by patients.Meanwhile, further research is recommended to investigate more topics in external therapy of TCM, such as the use of transdermal enhancer to improve drug absorption, the design of control group, etc.
- liver cirrhosis /
- hypertension, portal /
- endotoxemia /
- hepatic encephalopathy /
- ascites /
- TCM THERAPY /
- review

HTML全文

参考文献(19)

[1]BOS JD, MEINARDI MM.The 500 Dalton rule for the skin penetration of chemical compounds and drugs[J].Exp Dermatrol, 2000, 9 (3) :165-169.

[2]HUANG JR, SHI WQ, ZHU JZ, et al.Chronic hepatitis B and liver cirrhosis treat with medical instrument of DSG type I for hepatic diseases[J].Drug Eval, 2007, 4 (1) :37-39. (in Chinese) 黄建荣, 施维群, 朱菊珍, 等.DSG-I型电脑肝病治疗仪治疗慢性乙型肝炎和肝炎肝硬化[J].药品评价, 2007, 4 (1) :37

[3]SHI WQ, RU QJ, CAI GY, et al.Effect of umbilical sticking therapy with Qitou Xiaogu plaster in treating liver cirrhosis patients with portal hypertension[J].Chin J Integr Tradit West Med, 2008, 28 (7) :642-645. (in Chinese) 施维群, 茹清静, 蔡国英, 等.中药脐透消臌贴膏敷脐治疗肝硬化门静脉高压疗效观察[J].中国中西医结合杂志, 2008, 28 (7) :642-645.

[4]LIU GW, ZHAO WX, FEI JL, et al.Effects of Huoxue Sanjie recipe liver area application on portal vein hemodynamics in liver cirrhosis[J].Chin J Exp Tradit Med Formul, 2013, 19 (6) :298-300. (in Chinese) 刘光伟, 赵文霞, 费景兰, 等.活血散结方肝区封包对肝硬化门静脉系统血流动力学的影响[J].中国实验方剂学杂志, 2013, 19 (6) :298-300.

[5]SUN HC, GUO R, WANG ML.The clinical research on treating liver cirrhosis by Chinese medicine iontophoresis treatment[J].Hubei J Tradit Chin Med, 2010, 32 (3) :42-43. (in Chinese) 孙海潮, 郭锐, 王敏利.中药离子导入治疗肝炎肝硬化临床观察[J].湖北中医杂志, 2010, 32 (3) :42-43.

[6]TONG GD, ZHOU DQ, HE JS.Combined therapy of Shehuang paste and colonic dialysis with chinese medieines for treatment of refraetory cirrhotic ascites complieated with azotemia[J].Chin J Integr Tradit West Med, 2008, 28 (9) :788-792. (in Chinese) 童光东, 周大桥, 贺劲松.麝黄膏敷脐配合中药结肠透析治疗难治性肝硬化腹水合并氮质血症的临床研究[J].中国中西医结合杂志, 2008, 28 (9) :788-792.

[7]HE JS, ZHOU DQ, GAO H, et al.Clinical research on liver cirrbosis induced by hepatitis treated by medical instrument on hepatic diseases of type I DSG[J].Chin J Integr Tradit West Med on Liver, 2005, 15 (4) :234-236. (in Chinese) 贺劲松, 周大桥, 高辉, 等.DSG-Ⅰ型生物信息肝病治疗仪对肝炎肝硬化的影响[J].中西医结合肝病杂志, 2005, 15 (4) :234-236.

[8]RUAN P, GONG ZJ, ZHANG QR.Changes of plasma D (-) -lacate diamine oxidase and endotoxin inpatients with liver cirrhosis[J].Hepatobiliary Pancreat Dis Int, 2004, 3 (4) :456-462.

[9]HUANG SK, CHEN DX.Research advances in action mechanism of traditional Chinese medicine and its compound in treatment of endotoxemia[J].Jilin J Tradit Chin Med, 2012, 32 (6) :646-648. (in Chinese) 黄松科, 陈德兴.中药及复方治疗内毒素血症作用机制研究进展[J].吉林中医药, 2012, 32 (6) :646-648.

[10]SHI WQ, NI W.Clinical research of effect of umbilical Chinese materia medica paste on endotoxemia of cirrhosis patients[J].Chin J Tradit Chin Med Pharma, 2010, 25 (3) :452-455. (in Chinese) 施维群, 倪伟.中药脐部贴敷对肝硬化内毒素血症的影响[J].中华中医药杂志, 2010, 25 (3) :452-455.

[11]MA YP, ZHANG DZ, ZHANG XY, et al.The experimental research on rabbits with endoxtoxemic cirrhotic by retention enema of jieduguanchangye[J].Shanxi J Tradit Chin Med, 2012, 33 (11) :1558-1561. (in Chinese) 马羽萍, 张殿增, 张新昀, 等.解毒灌肠液干预肝硬化家兔内毒素血症的实验研究[J].陕西中医, 2012, 33 (11) :1558-1561.

[12]HU CH, SHI WQ.The clinical research on 61 patients with hepatic encephalopathy by retention enema to mixture of qingchuang[J].Zhejiang J Tradit Chin Med, 2007, 42 (7) :382-383. (in Chinese) 胡春华, 施维群.清肠合剂保留灌肠治疗肝性脑病61例临床观察[J].浙江中医杂志, 2007, 42 (7) :382-383.

[13]MENG QF.The clinical research on 35 patients with hepatic encephalopathy by the therpy of traditional Chinese medicine enema combined Xingnaojing injection on after colon dialysis[J].Sichuan J Tradit Chin Med, 2013, 31 (8) :110-111. (in Chinese) 孟青芳.结肠透析后中药灌肠联合醒脑静治疗肝性脑病35例[J].四川中医, 2013, 31 (8) :110-111.

[14]HUANG D, MAO DW, CHEN FH, et al.The clinical research on18 patients with hepatic encephalopathy by the therpy of tongfukaiqiao what from TCM[J].Henan J Tradit Chin Med, 2013, 33 (9) :1458-1459. (in Chinese) 黄丹, 毛德文, 陈风华, 等.通腑开窍法治疗肝性脑病18例[J].河南中医, 2013, 33 (9) :1458-1459.

[15]SHE SF, HOU JT, YANG XJ.The clinical research on hepatic encephalopathy what were treated to combine five therapies of TCM[J].J Anhui Univ Tradit Chin Med, 2010, 29 (4) :6-8. (in Chinese) 佘世锋, 侯江涛, 杨晓军.中医五联疗法治疗肝性脑病临床研究[J].安徽中医学院学报, 2010, 29 (4) :6-8.

[16]ZHANG LY.The clinical observation on 95 cases of cirrhotic ascites who were treated by combining traditional Chinese and western medicine[J].Chin Commun Doct, 2010, 12 (18) :137-138. (in Chinese) 张鲁豫.中西医结合治疗肝硬化腹水95例疗效观察[J].中国社区医师:医学专业, 2010, 12 (18) :137-138.

[17]CHI XL, JIANG JM, CHEN PQ, et al.The clinical observation on treatment of 30 cases of refractory cirrhosis ascites to the capsule what is prescription of enrichment of guzang plus Chinese medicine iontophoresis V[J].New J Tradit Chin Med, 2005, 37 (11) :40-41. (in Chinese) 池晓玲, 蒋俊民, 陈培琼, 等.浓缩臌胀胶囊加中药离子导入V号方治疗肝硬化难治性腹水30例疗效观察[J].新中医, 2005, 37 (11) :40-41.

[18]XU WJ, LI XH, GOU CY, et al.The clinical observation of using prescription of qing gan li dan to treated for 40 cases of cirrhotic ascites[J].Beijing J Tradit Chin Med, 2013, 32 (7) :522-524. (in Chinese) 许文君, 李秀惠, 勾春燕, 等.清肝利肠方灌肠治疗肝硬化腹水40例临床观察[J].北京中医药, 2013, 32 (7) :522-524.

[19]TIAN LY, DENG GY, WU Z, et al.The clinical studies of xiaozangling for point application treat on liver cirrhosis ascites[J].J Emerg Tradit Chin Med, 2012, 21 (11) :1742, 1780. (in Chinese) 田凌云, 邓桂元, 吴哲, 等.消胀灵穴位贴敷治疗肝硬化腹水临床研究[J].中国中医急症, 2012, 21 (11) :1742, 1780.

施引文献

资源附件(0)

访问统计