Progress in diagnosis and treatment of IgG4-related hepatobiliary diseases
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摘要:
IgG4相关性疾病是一类以淋巴浆细胞性炎症为主,伴血清和组织中IgG4增多并累及多器官或组织的慢性进行性全身性炎性疾病,累及肝胆胰腺系统时称之为IgG4相关肝胆疾病。简述了IgG4相关自身免疫性胰腺炎、IgG4相关硬化性胆管炎、IgG4相关自身免疫性肝炎的临床表现和实验室检查等方面。准确识别IgG4相关肝胆疾病的各个实验室结果,并正确诊断此类疾病,有助于避免不必要的手术和错误的治疗。
Abstract:IgG4- related diseases are a class of chronic, progressive, systemic inflammatory disorders that are characterized by lymphoplasmacytic inflammation, as well as elevated IgG4 levels in serum and tissue, and may involve multiple organs or tissues. When involving the pancreas, liver, and biliary tracts, they are called IgG4- related hepatobiliary diseases. IgG4- related autoimmune pancreatitis, IgG4- related sclerosing cholangitis, and IgG4- associated autoimmune hepatitis are reviewed in terms of their clinical manifestations and laboratory findings. Accurate identification of the laboratory results for IgG4- related hepatobiliary diseases and correct diagnosis of these diseases help to avoid unnecessary surgery and wrong treatment.
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