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Guidelines for the management of pancreatic neuroendocrine neoplasms (2014)
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摘要:
<正>胰腺神经内分泌肿瘤(pancreatic neuroendocrine neoplasms,p NEN),原称为胰岛细胞瘤,约占原发性胰腺肿瘤的3%。依据激素的分泌状态和患者的临床表现,分为功能性和无功能性p NEN。无功能性p NEN约占75%~85%;功能性p NEN常见的有胰岛素瘤和胃泌素瘤。胰岛素瘤一般位于胰腺,而胃泌素瘤多见于十二指肠或胰腺;其余的功能性p NEN均少见,统称
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Key words:
- pancreatic neoplasms /
- neuroendocrine tumors /
- therapy /
- guidebooks
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[1]STROSBERG J, GARDNER N, KVOLS L.Survival and prognostic factor analysis of 146 metastatic neuroendocrine tumors of the midgut[J].Neuroendocrinology, 2009, 89 (4) :471-476. [2]HASHIM YM, TRINKAUS KM, LINEHAN DC, et al.Regional lymphadenectomy is indicated in the surgical treatment of pancreatic neuroendocrine tumors (PNETs) [J].Ann Surg, 2014, 259 (2) :197-203. [3]MAYO SC, de JONG MC, PULITANO C, et al.Surgical management of hepatic neuroendocrine tumor metastasis:results from an international multi-institutional analysis[J].Ann Surg Oncol, 2010, 17 (12) :3129-3136. [4]CAPLIN ME, PAVEL M, C'WIKL'A JB, et al.Lanreotide in metastatic enteropancreatic neuroendocrine tumors[J].N Engl J Med, 2014, 371 (3) :224-233. [5]RAYMOND E, DAHAN L, RAOUL JL, et al.Sunitinib malate for the treatment of pancreatic neuroendocrine tumors[J].N Engl J Med, 2011, 364 (6) :501-513. -
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