Radiological evaluation after treatment of hepatocellular carcinoma: criteria and application
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摘要: 早期准确的疗效评价有助于临床医师决定是否继续或者改变现有治疗方案。简述了肿瘤疗效评价标准的发展过程;阐述了影像学评价标准在经局部介入或索拉非尼治疗肝细胞癌(HCC)中的应用,并对目前临床主要应用的4种影像学评价标准,即世界卫生组织(WTO)标准、实体瘤疗效评价标准(RECIST)、欧洲肝病学会(EASL)标准和mRECIST(modified RECIST)标准进行了比较,认为EASL和mRECIST标准优于WHO和RECIST标准,可以在早期时间点上预测HCC患者的预后情况。Abstract: An early and accurate response evaluation is essential for clinicians to decide whether to continue the treatment with current therapeutic regimen or to make necessary changes. This article briefly introduces the development of response evaluation criteria for tumors,elaborates on the application of radiological evaluation criteria in local interventional therapy or sorafenib treatment of hepatocellular carcinoma( HCC),compares the four radiological evaluation criteria,i. e.,World Health Organization( WHO) criteria,Response Evaluation Criteria in Solid Tumors( RECIST),European Association for the Study of Liver( EASL) criteria,and the modified RECIST( mRECIST),and thinks that EASL criteria and mRECIST are better than WHO criteria and RECIST and can predict the prognosis of HCC patients at earlier time points.
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Key words:
- carcinoma,hepatocellular /
- response evaluation /
- diagnostic imaging
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