Research advances in differential diagnosis of benign and malignant ascites
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摘要: 良恶性腹水的鉴别诊断对于明确病因、预后评价及治疗方案的确定均有重要价值。腹水的诊断方法很多,但至今尚无一种理想的方法能兼有高敏感度和特异度,同时满足临床经济学和可行性等要求。因此,寻找理想的腹水鉴别诊断方法已成为当前研究的重要课题。阐述了分子生物学检测、细胞学检查、肿瘤标志物联合检测、常规检测等诊断方法在良恶性腹水鉴别诊断中的临床应用价值,分析了相关生物学标志物的诊断效能,认为多指标联合检测可提高对良恶性腹水的鉴别诊断价值。Abstract: Differential diagnosis of benign and malignant ascites is of a great value in determining etiology,evaluating prognosis,and determining therapy regimens. There are many diagnostic methods for ascites,but up to now,no method can achieve high sensitivity and specificity and meet the requirements of clinical economics and feasibility at the same time. Therefore,searching for an ideal method for differential diagnosis of ascites has become an important topic of current research. This article describes the clinical value of diagnostic methods,such as molecular biological detection,cytological examination,combined determination of tumor markers,and routine tests,in the differential diagnosis of benign and malignant ascites,analyzes the diagnostic efficiency of related biomarkers,and points out that combined determination of various parameters has an increased value in the differential diagnosis of benign and malignant ascites.
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Key words:
- ascites /
- diagnosis /
- differential
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