Research advances in indicators for early diagnosis of liver cirrhosis patients with renal impairment
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摘要: 肝脏与肾脏关系密切,不同时期肝损伤均可发生不同程度及种类的肾脏疾病而导致肾损伤。此类肾损伤早期往往呈功能性,如果及时发现则可在药物作用下发生逆转,反之可发展为肝肾综合征或导致急性肾衰竭而危及生命。血清肌酐以及尿素氮等检测指标对肾损伤的早期诊断性能极为有限,难以达到对肝硬化患者合并肾损伤的早期监测及诊断。因此如何对肝硬化患者并发肾损伤进行早期监测,一直是该领域研究的热点。总结了近5年有关反映肾损伤早期检测指标的研究进展。Abstract: The liver is closely associated with the kidney,and liver injury in various stages can cause various kidney diseases to varying degrees,which further lead to renal impairment. Such renal impairment in the early stage is often functional and can be reversed by drugs,otherwise it can progress to hepatorenal syndrome,cause acute renal failure,and even threaten human life. The indicators such as serum creatinine and urea nitrogen have a limited effect in the early diagnosis of renal impairment and cannot be used for early monitoring and diagnosis of liver cirrhosis patients with renal impairment. Therefore,early monitoring of liver cirrhosis patients with renal impairment has always been a hot topic in this field. This article summarizes the research advances in the indicators for early diagnosis of renal impairment.
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Key words:
- liver cirrhosis /
- kidney diseases /
- diagnosis /
- review
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