Early nutrition support therapy for patients with severe acute pancreatitis
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摘要: 营养支持疗法在重症急性胰腺炎(SAP)的治疗中有着举足轻重的作用。总结了近年来SAP营养支持疗法方面的热点及新观点。肠黏膜屏障的损伤在胰腺炎的进展中发挥重要作用,肠内营养可保护肠黏膜屏障的功能,早期肠内营养可以明显降低患者病死率及并发症的发生率。SAP患者采用经鼻胃管途径进行营养支持,同鼻空肠管途径一样安全、有效。目前半要素或要素型肠内营养制剂的使用经验和临床研究尚不充分,免疫增强型肠内营养制剂及益生菌不作为常规推荐。Abstract: Nutrition support therapy plays an important role in the treatment of severe acute pancreatitis( SAP). This article reviews the hot topics and new ideas in nutrition support therapy for SAP in recent years. Damage of intestinal mucosal barrier plays an important role in the progression of pancreatitis. Enteral nutrition can protect the function of intestinal mucosal barrier and early enteral nutrition can significantly reduce patients' mortality rate and incidence rate of complications. Nutrition support for SAP patients via a nasogastric tube has comparable safety and effect to the nutrition support via a nasojejunal tube. At present,there are no enough experience and clinical studies on semi- elemental or elemental enteral nutrition preparations,and immune- enhancing enteral nutrition preparations and probiotics are not recommended as conventional means.
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Key words:
- pancreatitis /
- nutritional support /
- therapy
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