Application of needle- based confocal laser endomicroscopy in diagnosis of pancreatic cystic lesions
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摘要: 胰腺囊性病变(PCLs)的病理类型多样,生物学行为差异极大,其预后各不相同。目前的诊断主要依据患者的病史、临床表现、影像学检查、血清学检查以及细针穿刺活组织检查、囊液细胞学检查综合分析。细针型共聚焦激光显微内镜是一种新型显微内镜,其可与19 G穿刺针匹配应用,在超声内镜引导下对PCLs在体实时显示病变组织细胞、亚细胞结构,进而实现对PCLs的准确诊断。对细针型共聚焦激光显微内镜在诊断PCLs中的应用进行了概述。Abstract: Pancreatic cystic lesions( PCLs) have various pathological types,extremely different biological behaviors,and different prognosis. Current diagnosis of PCLs mainly depends on a comprehensive analysis of the patient's medical history,clinical manifestations,imaging examinations,serological examinations,fine needle aspiration biopsy,and cytological examination of cyst fluid. Needle- based confocal laser endomicroscopy( n CLE) is a novel method of microscopic endoscopy and is compatible with 19- gauge puncture needle. Under the guidance of endoscopic ultrasound,n CLE can achieve real- time in vivo imaging of the cellular and subcellular structures of diseased tissues and thus helps with the accurate diagnosis of PCLs. This article reviews the application of n CLE in the diagnosis of PCLs.
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Key words:
- pancreatic cyst /
- microscopy /
- confocal
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