Selective portal vein embolization:theoretical basis and clinical application
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摘要: 目前,手术切除部分肝叶仍然是治疗肝脏原发性或转移性恶性肿瘤首选和最有效的方法,然而术后残余肝脏容积不足容易发生肝衰竭,影响预后。选择性门静脉栓塞术通过栓塞荷瘤侧门静脉分支,从而使门静脉血流重分配,增加对侧肝组织的门静脉血流,来增加余留肝脏体积。综述了选择性门静脉栓塞术的理论基础及其在临床中的应用,作为肝切除术前的辅助治疗方法,降低术后肝衰竭发生率,提高肿瘤切除率和手术的安全性,使原来无法行手术治疗的患者得到了手术的机会。Abstract: At present, partial hepatolobectomy remains the preferred and most effective treatment method for primary or metastatic malignant liver tumors, but a low future liver remnant (FLR) volume after surgery is the main risk factor for liver failure and may affect patients' prognosis.Through the embolization of the tumor-bearing portal vein branch, selective portal vein embolization (PVE) redistributes the portal vein blood flow and increases portal vein blood flow in the contralateral liver tissue to increase the FLR volume.This article reviews the theoretical basis and clinical application of selective PVE.As an adjuvant therapy before hepatectomy, selective PVE can reduce the incidence rate of postoperative liver failure, increase tumor resection rate and surgical safety, and create the chance for surgery in patients who cannot undergo surgical treatment.
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Key words:
- liver neoplasms /
- portal vein embolization /
- hepatectomy /
- review
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