江苏省启东市HBV感染相关疾病住院患者的经济负担及对家庭经济的影响

姚红玉; 王宇婷; 唐红萍; 黄慧瑶; 张红健; 沙春霞; 石菊芳; 代敏; 陈陶阳; 曲春枫

doi:10.3969/j.issn.1001-5256.2017.05.012

江苏省启东市HBV感染相关疾病住院患者的经济负担及对家庭经济的影响

DOI: 10.3969/j.issn.1001-5256.2017.05.012

1. 启东市人民医院&启东肝癌防治研究所科研科
2. 国家癌症中心/中国医学科学院北京协和医学院肿瘤医院免疫学研究室
3. 国家癌症中心/中国医学科学院北京协和医学院肿瘤医院城市癌症早诊早治项目办公室
4. 启东市传染病医院
5. 启东市人民医院&启东肝癌防治研究所病因室

基金项目:

“十二五”传染病国家科技重大专项(2012ZX10002008-001,003)；江苏省科技支撑计划(BE2013657)；

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中图分类号: R512.62;R197.3
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出版历程
- 出版日期: 2017-05-20

Economic burden of inpatients with hepatitis B virus infection-related diseases and its impact on family financial status in Qidong, Jiangsu Province, China

Department of Research Administration, Qidong People′s Hospital & Qidong Liver Cancer Institute

Research funding:

摘要

摘要:
目的分析江苏省启东市HBV感染相关疾病住院患者（包括原发性肝癌、乙型肝炎肝硬化和慢性乙型肝炎）的经济负担以及患病对家庭经济的影响。方法采用时间段连续病例整群随机抽样方法,抽取江苏省启东市（县级市）人民医院及启东市传染病医院2014年5月1日-2015年3月31日收治的HBV感染相关疾病住院患者,通过问卷调查收集其人口社会学信息、临床信息、近3年的直接医疗费用、直接非医疗费用、因患病所致的误工损失及患病对家庭经济的影响。采用Wilcoxon秩和检验或KruskalWallis H秩和检验分析疾病临床分期、年龄、性别、受教育程度、职业、医保类型、家庭收入等因素对经济负担的影响。通过χ2检验或Fisher精确检验分析HBV感染后不同疾病类型住院患者家庭经济压力的差异。结果 HBV相关原发性肝癌、乙型肝炎肝硬化、慢性乙型肝炎住院患者近3年的经济负担总和分别为94 001元、63 421元和39 360元;其中直接医疗费用分别占84.7%、83.6%和89.9%;近1年的自付费用分别占家庭年收入的99.6%、59.4%和16.7%。3组患者自述经济压力很大比例之间比较,差异...
- 肝肿瘤 /
- 肝硬化 /
- 肝炎,乙型,慢性 /
- 肝炎病毒,乙型 /
- 患病代价
Abstract:
Objective To investigate the economic burden of inpatients with hepatitis B virus (HBV) infection-related diseases (including primary liver cancer, hepatitis B cirrhosis, and chronic hepatitis B) and its impact on family financial status in Qidong, Jiangsu Province, China.Methods Cluster random sampling was used to select consecutive cases of HBV infection-related diseases who were hospitalized in The People's Hospital of Qidong and Qidong Hospital for Infectious Diseases from May 1, 2014 to March 31, 2015.A questionnaire survey was performed to collect their demographic data, clinical data, direct medical costs within the past three years, direct non-medical costs, loss of income due to missed work, and the impact of disease on family financial status.The Wilcoxon rank sum test or the Kruskal-Wallis H rank sum test was used to analyze the impact of various factors on economic burden, such as clinical stage, age, sex, educational level, occupation, type of medical insurance, and family income.The chi-square test or Fisher's exact test was used to analyze the difference in family economic pressure caused by different disease types after HBV infection.Results The total costs of primary liver cancer, hepatitis B cirrhosis, and chronic hepatitis B within the past three years were 94001 yuan, 63421 yuan, and 39360 yuan, respectively, and direct medical costs accounted for 84.7%, 83.6%, and 89.9%, respectively.The self-paid costs within the past one year accounted for99.6%, 59.4%, and 16.7%, respectively, of the annual family income.There was a significant difference in the proportion of patients with great economic pressure between the three groups (38.7% vs 43.1% vs 11.3%, χ2=30.066, P<0.001) .There were also significant differences in the number of missed working days and loss of income due to missed work (7903 yuan vs 6280 yuan vs 2600 yuan, χ2=68.601, P<0.001) .Conclusion HBV infection-related diseases bring considerable burden to inpatients and their families, and the economic burden increases with a longer course of disease and more serious conditions.With the progression of chronic hepatitis B to hepatitis B cirrhosis and primary liver cancer, diseases impose greater economic pressure on families, and patients themselves and their relatives may suffer from greater loss of income due to missed work.Prevention and control of HBV infection has great social and economic benefits.
- liver neoplasms /
- liver cirrhosis /
- hepatitis B, chronic /
- hepatitis B virus /
- cost of illness

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参考文献(9)

[1]LIANG XF, BI SL, YANG WZ, et al.Epidemiological serosurvey of hepatitis B in China-declining HBV prevalence due to hepatitis B vaccination[J].Vaccine, 2009, 27 (47) :6550-6557.

[2] Ministry of Health of the People’s Republic of China.Diagnosis, management, and treatment of hepatocellular carcinoma (V2011) [J].J Clin Hepatol, 2011, 27 (11) :1141-1159. (in Chinese) 中华人民共和国卫生部.原发性肝癌诊疗规范 (2011年版) [J].临床肝胆病杂志, 2011, 27 (11) :1141-1159.

[3] Chinese Society of Hepatology, Chinese Society of Infectious Diseases, Chinese Medical Association.The guideline of prevention and treatment for chronic hepatitis B (2010 version) [J].J Clin Hepatol, 2011, 27 (1) :Ⅰ-ⅩⅥ. (in Chinese) 中华医学会肝病学分会, 中华医学会感染病学分会.慢性乙型肝炎防治指南 (2010版) [J].临床肝胆病杂志, 2011, 27 (1) :Ⅰ-ⅩⅥ.

[4]Chinese Society of Infectious Diseases and Parasitology, Chinese Society of Hepatology, Chinese Medical Association.Prevention and treatment of viral hepatitis[J].Chin J Infect Dis, 2001, 19 (1) :56-62. (in Chinese) 中华医学会传染病与寄生虫病学分会、肝病学分会.病毒性肝炎防治方案[J].中华传染病杂志, 2001, 19 (1) :56-62.

[5]HU SL.Research on disease burden[J].Health Economics Research, 2005, 5:22-27. (in Chinese) 胡善联.疾病负担的研究[J].卫生经济研究, 2005, 5:22-27.

[6]LIANG S, ZHANG SX, MA QS, et al.Financial burden of hepatitis B-related diseases and factors influencing the costs in Shenzhen, China[J].Chin J Epidemiol, 2010, 31 (12) :1340-1345. (in Chinese) 梁森, 张顺祥, 马起山, 等.深圳市乙型肝炎相关疾病经济负担及其影响因素分析[J].中华流行病学杂志, 2010, 31 (12) :1340-1345.

[7]LYU JJ, XU AQ, WANG J, et al.Direct economic burden of hepatitis B virus related diseases evidence from Shandong, China[J].BMC Health Serv Res, 2013, 13 (1) :37.

[8]LYU JJ, LI RP, XU AQ, et al.Economic burden and related factors on inpatients with HBV-related diseases in Shandong province[J].Chin J Epidemiol, 2013, 34 (3) :267-272. (in Chinese) 吕静静, 李仁鹏, 徐爱强, 等.山东省乙型肝炎病毒感染相关疾病住院患者经济负担及影响因素分析[J].中华流行病学杂志, 2013, 34 (3) :267-272.

[9]MA QS, ZOU YH, ZHANG SX, et al.Estimation on the intangible cost and influencing factors for patients with hepatitis B-related diseases[J].Chin J Epidemiol, 2011, 32 (8) :764-767. (in Chinese) 马起山, 邹宇华, 张顺祥, 等.广州市乙型肝炎相关疾病住院病例无形费用及其影响因素分析[J].中华流行病学杂志, 2011, 32 (8) :764-767.

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