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血清降钙素原检测对肝衰竭合并感染的早期诊断价值

王传敏 孟忠吉 陈悦 刘莉

王传敏, 孟忠吉, 陈悦, 刘莉. 血清降钙素原检测对肝衰竭合并感染的早期诊断价值[J]. 临床肝胆病杂志, 2017, 33(6): 1137-1140. DOI: 10.3969/j.issn.1001-5256.2017.06.024.
引用本文: 王传敏, 孟忠吉, 陈悦, 刘莉. 血清降钙素原检测对肝衰竭合并感染的早期诊断价值[J]. 临床肝胆病杂志, 2017, 33(6): 1137-1140. DOI: 10.3969/j.issn.1001-5256.2017.06.024.
Wang ChuanMin, Meng ZhongJi, Chen Yue, Liu Li. Value of serum PCT in early diagnosis of bacterial infection in patients with liver failure[J]. J Clin Hepatol, 2017, 33(6): 1137-1140. DOI: 10.3969/j.issn.1001-5256.2017.06.024.
Citation: Wang ChuanMin, Meng ZhongJi, Chen Yue, Liu Li. Value of serum PCT in early diagnosis of bacterial infection in patients with liver failure[J]. J Clin Hepatol, 2017, 33(6): 1137-1140. DOI: 10.3969/j.issn.1001-5256.2017.06.024.

血清降钙素原检测对肝衰竭合并感染的早期诊断价值

DOI: 10.3969/j.issn.1001-5256.2017.06.024
基金项目: 

湖北省卫生计生委资助项目(WJ2015MB224); 

详细信息
  • 中图分类号: R575

Value of serum PCT in early diagnosis of bacterial infection in patients with liver failure

Research funding: 

 

  • 摘要:

    目的探讨血清降钙素原(PCT)检测对于肝衰竭合并感染早期诊断的价值。方法选取2014年1月-2014年12月十堰市太和医院463例乙型肝炎患者,按肝功能指标分为轻度肝损伤组(n=120)、中度肝损伤组(n=222)、重度肝损伤组(n=53)和肝衰竭组(n=68),对各组PCT水平进行检测,对肝衰竭患者进一步测定WBC、高敏C反应蛋白(hs CRP)并观察临床表现。计量资料符合正态分布组间比较采用t检验,不符合正态分布的多组间比较采用Kruskal-Wallis H检验,组间两两比较采用Mann-Whitney U检验;计数资料组间比较采用χ2检验;预测分析采用受试者工作特征曲线(ROC曲线)法。结果肝衰竭组PCT水平[0.81(0.342.15)]明显高于重度肝损伤组[0.53(0.211.59)]、中度肝损伤组[0.35(0.101.18)]及轻度肝损伤组[0.17(0.100.60)],组间比较差异有统计学意义(χ2=25.091,P<0.05)。肝衰竭患者中PCT<0.25 ng/...

     

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