病毒性肝炎神经系统并发症的研究进展

韩帅; 张野

doi:10.3969/j.issn.1001-5256.2017.06.031

病毒性肝炎神经系统并发症的研究进展

DOI: 10.3969/j.issn.1001-5256.2017.06.031

韩帅,
张野

1. 第四军医大学学员一旅
2. 第四军医大学唐都医院全军感染病中心

详细信息

中图分类号: R512.6;R747.9
计量
- 文章访问数: 2091
- HTML全文浏览量: 31
- PDF下载量: 436
- 被引次数: 0
出版历程
- 出版日期: 2017-06-20

Research advances in neurological complications of viral hepatitis

Han Shuai,
Zhang Ye

摘要

摘要: 病毒性肝炎引起的神经系统并发症包括肝性脑病、肝性脊髓病、周围神经病、脑膜脑炎和癫痫等。肝性脑病是主要、常见的并发症,其诊断和治疗手段相对成熟,而其他并发症相对少见,治疗方面也尚未完善。主要介绍各并发症的分类、临床表现及治疗进展,并对其发生机制的研究进展进行总结,以期为病毒性肝炎神经系统并发症寻找一条最佳的治疗途径。
- 肝炎,病毒性,人 /
- 神经系统疾病 /
- 综述
Abstract: Neurological complications of viral hepatitis mainly include hepatic encephalopathy, hepatic myelopathy, peripheral neuropathy, meningoencephalitis, and epilepsy. Hepatic encephalopathy is a common complication with mature diagnosis and treatment methods, and the other complications are relatively uncommon and lack treatment methods. This article introduces the classification, clinical manifestation, and treatment of each complication, in order to find the optimal therapies for neurological complications of viral hepatitis.
- hepatitis, viral, human /
- nervous system diseases /
- review

HTML全文

参考文献(24)

[1]ZHAO K, ZHANG YX.Treatment of minimal hepatic encephalopathy[J].J Clin Hepatol, 2014, 30 (4) :108-110. (in Chinese) 赵凯, 张跃新.轻微肝性脑病的治疗现状[J].临床肝胆病杂志, 2014, 30 (4) :108-110.

[2]VILSTRUP H, AMODIO P, BAJAJ J, et al.Hepatic encephalopathy in chronic liver disease:2014 practice guideline by the American Association for the Study of Liver Diseases and the Study of Liver Diseases and the European Association for the Study of the Liver[J].Hepatology, 2014, 60 (2) :715-735.

[3]MENDOZA G, MARTIFABREGAS J, KULISEVSKY J, et al.Hepatic myelopathy:a rare complication of portocaval shunt[J].Eur Neurol, 1994, 34 (4) :209-212.

[4]BEZERRA ML, HARUMI JA, SHINOSAKI JS, et al.Hepatitis C virus:a rare manifestation-remitting relapsing central and peripheral demyelination[J].Neurol India, 2011, 59 (1) :114-116.

[5]XU CL, WANG DX.Peripheral neuropathy associated with viral hepatitis[J].China J Contempt Neuron Neurosurg, 2012, 12 (4) :480-482. (in Chinese) 许春伶, 王得新.病毒性肝炎伴发周围神经病变[J].中国现代神经疾病杂志, 2012, 12 (4) :480-482.

[6]CHENG DY, WANG XM, OU WN, et al.Clinical analysis literature review on 7 cases with liver diseases complicated by GuillainBarre syndrome and related literature review[J/CD].Chin J Exp Clin Infect Dis:Electronic Edition, 2014, 8 (3) :387-390. (in Chinese) 程丹颖, 王笑梅, 欧蔚妮, 等.肝病合并格林-巴利综合征七例临床分析及文献复习[J/CD].中华实验和临床感染病杂志:电子版, 2014, 8 (3) :387-390.

[7]PERMKUMAR M, BAGCHI A, KAPOOR N, et al.Hepatic myelopathy in and a patient with decompensated alcoholic cirrhosis and portal colopathy[J].Case Reports Hepatol, 2012, 2012:735906.

[8]SUREKA B, BANSAL K, PATIDAR Y, et al.Neurologic manifestations of chronic liver disease and liver cirrhosis[J].Curr Prob Diagn Radiol, 2015, 44 (5) :449-461.

[9]CASH WJ, Mc CONVILLE P, Mc DERMOTT E, et al.Current concepts in the assessment and treatment of hepatic encephalopathy[J].QJM, 2010, 103 (1) :9-16.

[10]FERRO JM, VIANA P, SANTOS P.Management of neurologic manifestations in patients with liver disease[J].Curr Treat Options Neurol, 2016, 18 (8) :37.

[11]ABID S, JAFRIW, MUMTAZ K, et al.Efficacy of L-omithineL-aspartate as an adjuvant therapy in cirrhotic patients with hepatic encephalopathy[J].J Coll Physicians Surg Pak, 2011, 21 (11) :666-671.

[12]KHAN AA, SHAIK MV, PARVEEN N, et al, Human fetal liver derived stem cell transplantation as supportive modality management of end stage decompensated liver cirrhosis[J].Cell Transplant, 2010, 47 (1) :1.

[13]RUGGERO MA, ARGENTO AC, HEAVNER MS, et al.Molecular Adsorbent Recalculating System (MARS) removal of piperaoillin/tazobactam in a patient with acetaminophen-induced acute liver failure[J].Transpl Infect Dis, 2013, 15 (2) :214-218.

[14]GARCOVICH M, ZOCCO MA, ROCCARINA D, et al.Prevention and treatment of hepatic encephalopathy:focusing on gut microbiota[J].World J Gastroenterology, 2012, 18 (46) :6693-6700.

[15]BAJAJ JS, HEUMAN DM, HYLEMON PB, et al.Randomized clinical trial:lactobacillus GG modulates gut micro biome, metabolome and end toxemia in patients with cirrhosis[J].Aliment Pharmacol Ther, 2014, 39 (10) :1113-1125.

[16]BUTTERWORTH R.Metal toxicity liver disease and neurodegeneration[J].Neurotox Res, 2010, 18 (1) :100-105.

[17]NARDONE R, HOLLER Y, THOMSCHEWSKI A, et al.Central motor conduction studies in patients with spinal cord disorders:a review[J].Spinal Cord, 2014, 52 (6) :420-427.

[18]YANG Y, YANG L.Research progress in hepatic myelopathy[J].J Clin Hepatol, 2015, 31 (12) :2097-2099. (in Chinese) 杨阳, 杨龙.肝性脊髓病研究进展[J].临床肝胆病杂志, 2015, 31 (12) :2097-2099.

[19]PAN YP, FAN N, LI M.Advances in research of hepatic myelopathy[J].Chin J Disaster Med, 2014, 2 (12) :710-712. (in Chinese) 潘宜鹏, 范宁, 李明.肝性脊髓病研究现状[J].中华灾害救援医学, 2014, 2 (12) :710-712.

[20]QI HY, XIAO ZY, WANG YX, et al.Clinical analysis and discuss of the possible pathogenesis of hepatic myelopathy[J].Occup Health, 2008, 24 (1) :1979-1980. (in Chinese) 歧红阳, 肖占宇, 王云溪, 等.肝性脊髓病的临床分析及可能发病机制[J].职业与健康, 2008, 24 (1) :1979-1980.

[21]SCHREIBER AL, NORBURY JW, de SOUSA EA.Functional recovery of untreated human immunodeficiency virus-associated Guillain-Barre syndrome:a case report[J].Ann Phys Rehabil Med, 2011, 54 (8) :519-524.

[22]MALAGUARNERA M, GARGANTE MP, MALAGUARNERA G, et al.Bifid bacterium combined with fructo-oligosaccharide versus lacunose in the treatment of patients with hepatic encephalopathy[J].Eur J Gastroenterol Heaton, 2010, 22 (2) :199-206.

[23]ZHAO YL.The analysis of clinical therapeutic efficacy on 29 cases of hepatic myelopathy[J].Chin Prac Med, 2011, 6 (6) :100-101. (in Chinese) 赵宇亮.肝性脊髓病29例临床疗效分析[J].中国实用医药, 2011, 6 (6) :100-101.

[24]CHIN RL, SANDER HW, BRANNAGAN TH, et al.Demyelinating neuropathy in patients with hepatitis C Virus infection[J].J Clin Neuromuscular Dis, 2010, 11 (4) :209-212.

施引文献

资源附件(0)

访问统计