Management algorithm for interrupting mother-to-child transmission of hepatitis B
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摘要:
<正>母婴传播是HBV的重要传播途径,加强慢性HBV感染孕妇及其所分娩婴儿的规范化管理是切断母婴传播的有效途径,为规范我国HBV母婴阻断临床管理,我们组织感染病学、肝病学、免疫学与产科学专家参照国内外公认乙型肝炎防治指南[1-5]和最新研究成果[6-8]形成《乙型肝炎母婴阻断临床管理流程》,包括从初次产检的筛查到婴儿乙型肝炎免疫接种效果的评价,共10个连续的环节。
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Key words:
- hepatitis B /
- mother-to-child transmission /
- clinical management /
- consensus
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[1]Chinese Society of Hepatology and Chinese Society of Infectious Diseases, Chinese Medical Association.The guideline of prevention andtreatment for chronic hepatitis B:a 2015 update[J].J Clin Hepatol, 2015, 31 (12) :1941-1960. (in Chinese) 中华医学会肝病学分会, 中华医学会感染病学分会.慢性乙型肝炎防治指南 (2015年更新版) [J].临床肝胆病杂志, 2015, 31 (12) :1941-1960. [2] Chinese Society of Gynecology and Obstetrics, Chinese Medical Association.The guideline of prevention for mother-to-child transmission of hepatitis B[J].Chin J Obstet Gynecol, 2013, 48 (2) :151-154. (in Chinese) 中华医学会妇产科学分会产科学组.乙型肝炎病毒母婴传播预防临床指南[J].中华妇产科杂志, 2013, 48 (2) :151-154. [3]TERRAULT NA, BZOWEJ NH, CHANG KM, et al.AASLDguidelines for treatment of chronic hepatitis B[J].Hepatology, 2016, 63 (1) :261-283. [4] SARIN SK, KUMAR M, LAU GK, et al.Asian-Pacific clinical practice guidelines on the management of hepatitis B:a 2015 update[J].Hepatol Int, 2016, 10 (1) :1-98. [5]European Association for the Study of the Liver.EASL clinical practice guidelines:management of chronic hepatitis B virus infection[J].J Hepatol, 2012, 57 (1) :167-185. [6]ZHANG H, PAN C, PANG Q, et al.Telbivudine or lamivudine use in late pregnancy safely reduces perinatal transmission of hepatitis B virus in real-life practice[J].Hepatology, 2014, 60 (2) :468-476. [7]HAN GR, CAO MK, ZHAO W, et al.A prospective and open-label study for the efficacy and safety of telbivudine in pregnancy for the prevention of perinatal transmission of hepatitis B virus infection[J].JHepatol, 2011, 55 (6) :1215-1221. [8]PAN CQ, DUAN Z, DAI E, et al.Tenofovir to prevent hepatitis Btransmission in mothers with high viral load[J].N Engl J Med, 2016, 374 (24) :2324-2334. [9]National Health and Family Planning Commission of the People's Republic of China.Action plan to prevent mother-to-child transmission of AIDS, syphilis, and hepatitis B (2015) [EB/OL]//http://www.nhfpc.gov.cn/ewebeditor/uploadfile/2015/06/20150615151817186.docx. (in Chinese) 国家卫生和计划生育委员会.预防艾滋病、梅毒和乙型肝炎母婴传播工作实施方案 (2015年版) [EB/OL]//http://www.nhfpc.gov.cn/ewebeditor/uploadfile/2015/06/20150615151817186.docx. [10]WANG J, ZHU Q, ZHANG X.Effect of delivery mode on maternalinfant transmission of hepatitis B virus by immunoprophylaxis[J].Chin Med J (Engl) , 2002, 115 (10) :1510-1512. [11]HU Y, CHEN J, WEN J, et al.Effect of elective cesarean section on the risk of mother-to-child transmission of hepatitis B virus[J].BMC Pregnancy Childbirth, 2013, 13:119. [12]MAST EE, MARGOLIS HS, FIORE AE, et al.Hepatitis B vaccination recommendations for infants, children, and adolescents[J].MMWR, 2005, 54 (RR-16) :1-23. [13]BENABOUD S, PRUVOST A, COFFIE PA, et al.Concentrations of tenofovir and emtricitabine in breast milk of HIV-1-infected women in Abidjan, Cote d'Ivoire, in the ANRS 12109 TEm AAStudy, Step 2[J].Antimicrob Agents Chemother, 2011, 55 (3) :1315-1317.
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