IgG4相关性硬化性胆管炎的研究现状

李雨涵; 向晓星

doi:10.3969/j.issn.1001-5256.2017.11.042

IgG4相关性硬化性胆管炎的研究现状

DOI: 10.3969/j.issn.1001-5256.2017.11.042

1. 大连医科大学消化内科
2. 苏北人民医院消化内科

详细信息

中图分类号: R575.7
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出版历程
- 收稿日期: 2017-07-24
- 出版日期: 2017-11-20

Research advances in immunoglobulin G4-related sclerosing cholangitis

Department of Gastroenterology, Dalian Medical University

摘要

摘要: IgG4相关性硬化性胆管炎（IgG4-SC）是新近发现的一类发病机制不明的继发性硬化性胆管炎。以血清IgG4浓度升高、慢性进行性梗阻性黄疸、组织结构中大量IgG4阳性浆细胞和淋巴细胞弥漫或局限性浸润、纤维化和闭塞性静脉炎为特征。综述了IgG4-SC的诊断、治疗以及其与原发性硬化性胆管炎和胆管癌之间的关系。
- 免疫球蛋白G /
- 胆管炎,硬化性 /
- 综述
Abstract: Immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) is a new type of secondary sclerosing cholangitis which was discovered recently and has unknown pathogenesis.IgG4-SC is characterized by an increased serum level of immunoglobulin G4 (IgG4) , chronic progressive obstructive jaundice, diffuse or local infiltration of a large number of IgG4-positive plasma cells and lymphocytes, fibrosis, and obstructive phlebitis.This article reviews the diagnosis and treatment of IgG4-SC and its association with primary sclerosing cholangitis and cholangiocarcinoma.
- immunoglobulin G /
- cholangitis, sclerosing /
- review

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参考文献(41)

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