The critical importance of diagnosing and treating liver fibrosis
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摘要: 肝纤维化是各种病因引起慢性反复肝损伤后的疤痕修复反应,是肝硬化发生的早期、可逆阶段。概述了肝纤维化与肝硬化的区别和慢性肝病的分期方法,重点论述了肝纤维化早期诊治的重要性,介绍了目前早期诊断评估方法以及肝纤维化的药物开发与治疗进展。强调肝纤维化患者的诊断及治疗对防止肝病进展为失代偿期肝硬化具有重要意义。Abstract: Liver fibrosis is the scar repairing reaction in response to chronic liver injury due to various etiologies. It has been considered as the early and reversible stage of liver cirrhosis. This article points out the distinction between liver fibrosis and cirrhosis, introduces the current staging system of chronic liver diseases, and recent progress in diagnosing and evaluating liver fibrosis, as well as the medical treatment.The critical importance of diagnosing and treating liver fibrosis in preventing liver diseases progression into decompensated liver cirrhosis is emphasized.
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Key words:
- liver cirrhosis /
- diagnosis /
- therapy
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