非酒精性脂肪性肝病相关肝硬化的自然史与临床特点

张霞霞; 徐宏团; 徐有青

doi:10.3969/j.issn.1001-5256.2018.01.004

非酒精性脂肪性肝病相关肝硬化的自然史与临床特点

DOI: 10.3969/j.issn.1001-5256.2018.01.004

1. 首都医科大学附属北京天坛医院消化内科
2. 江苏省连云港市赣榆区人民医院

详细信息

中图分类号: R575
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出版历程
- 出版日期: 2018-01-20

The natural history and clinical features of nonalcoholic fatty liver disease-related cirrhosis

Department of Gastroenterology, Tiantan Hospital, Capital Medical University, Beijing 100050, China

摘要

摘要: 非酒精性脂肪性肝病(NAFLD)是一种与胰岛素抵抗和遗传易感性密切相关的代谢性肝损伤,包括非酒精性单纯性脂肪肝、非酒精性脂肪性肝炎及其相关肝硬化和肝细胞癌,现已成为日益严峻的公共健康问题。阐述了NAFLD较独特的自然史及NAFLD相关肝硬化疾病的临床特点。未来需进一步加强NAFLD相关肝硬化进展机制的探究,有效预防疾病进展为肝硬化,从而减少肝脏相关死亡事件,减轻公共健康相关经济负担。
- 非酒精性脂肪性肝病 /
- 肝硬化 /
- 疾病特征
Abstract: Nonalcoholic fatty liver disease ( NAFLD) is a type of metabolic liver injury closely associated with insulin resistance and genetic susceptibility and includes nonalcoholic simple fatty liver, nonalcoholic steatohepatitis, liver cirrhosis, and hepatocellular carcinoma. It has become an important public health issue nowadays. This article elaborates on the unique natural history of NAFLD and the clinical features of NAFLD-related cirrhosis. Further research on the progression of NAFLD-related cirrhosis is needed in the future to prevent the progression to liver cirrhosis, reduce liver-related death events, and relieve the economic burden for public health.
- nonalcoholic fatty liver disease /
- liver cirrhosis /
- disease attributes

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参考文献(26)

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