Prednisolone combined with hyperbaric oxygen used to control radiation-induced gastritis after radiotherapy for hepatocellular carcinoma: a case report
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摘要:
<正>放射性胃炎是较少见的一类肿瘤放疗后并发症,随着放射治疗在肝癌、食管癌、胰腺癌、胆管癌等上腹部肿瘤中的应用,作为相邻器官的胃、十二指肠也会受到一定剂量的照射,胃肠组织的耐受剂量为45~55 Gy[1],当大于这个剂量时会造成胃肠黏膜放射性损伤,引起一系列的消化道症状,如厌食、恶心、呕吐、腹胀等,重者可引起消化道出血[2]。吉林大学第一医院收治1例肝细胞癌放疗后出现消化道出血患者,经治疗后病情
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Key words:
- carcinoma, hepatocellular /
- gastritis /
- radiation injuries /
- hormones /
- hyperbaric oxygenation /
- case reports
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[1]WEI HL, ZHOU P, GUO XP.Current understanding of radiationinduced gastroduodenal injury[J].Mod Oncol, 2016, 24 (9) :1476-1479. (in Chinese) 魏华琳, 周平, 郭小陪.放射性胃、十二指肠损伤的研究现状[J].现代肿瘤医学, 2016, 24 (9) :1476-1479. [2]WANG J, ZHAO ZG, NI XD, et al.Clinical efficacy of laparoscopic surgery for pelvic radiation induced enteritis[J].Chin J Dig Surg, 2017, 16 (7) :720-724. (in Chinese) 王剑, 赵振国, 倪小冬, 等.腹腔镜手术治疗放射性肠损伤的临床疗效[J].中华消化外科杂志, 2017, 16 (7) :720-724. [3]INDARAM AV, VISVALINGAM V, LOCKE M, et al.Mucosal cytokine production in radiation-induced proctosigmoiditis compared with inflammatory bowel disease[J].Am J Gastroenterol, 2000, 95 (5) :1221-1225. [4]HALL EJ.Radiobiology for the radiologist[M].Philadelphia:Lippincott Williams&Wilkins, 2000:165-167. [5]BISMAR MM, SINICROPE FA.Radiation enteritis[J].Curr Gastroenterol Rep, 2002, 4 (5) :361-365. [6]SELL A, JENSEN TS.Acute gastric ulcers induced by radiation[J].Acta Radiol Ther Phys Biol, 1966, 4 (4) :289-297. [7]TAKATORI K, TERASHIMA K, YOSHIDA R, et al.Upper gastrointestinal complications associated with gemcitabine-concurrent proton radiotherapy for inoperable pancreatic cancer[J].J Gastroenterol, 2014, 49 (6) :1074-1080. [8]SU L, WANG Z, HUANG F, et al.Effect of glycyrrhetinic acid attenuating radiation-induced inflammation and its mechanism[J].Chin J Clin Pharmacol Ther, 2016, 21 (10) :1088-1094. (in Chinese) 苏丽, 王锃, 黄菲, 等.甘草次酸减轻放射性炎症反应的作用机制研究[J].中国临床药理学与治疗学, 2016, 21 (10) :1088-1094. [9]ZHANG L, XIE XY, WANG Y, et al.Treatment of radiation-induced hemorrhagic gastritis with prednisolone:a case report[J].World J Gastroenterol, 2012, 18 (48) :7402-7404. [10]TOYODA H, JARAMILLO E, MUKAI K, et al.Treatment of radiation-induced hemorrhagic duodenitis with argon plasma coagulation[J].Endoscopy, 2004, 36 (2) :192. [11]KERNSTINE KH, GREENSMITH JE, JOHLIN FC, et al.Hyperbaric oxygen treatment of hemorrhagic radiation-induced gastritis after esophagectomy[J].Ann Thorac Surg, 2005, 80 (3) :1115-1117.
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