A case of systemic light - chain amyloidosis
-
摘要:
<正>1病例资料患者女性,54岁,因"间歇性乏力、口干4个月,加重2个月"入本院。患者缘于4个月前无明显诱因出现间歇性乏力、口干,偶有上腹胀痛,于当地医院行PET-CT检查,提示甲状腺结节,给予优甲乐治疗,乏力、口干症状未见明显缓解。2个月前出现乏力、口干加重,睡眠及饮食差,近4个月体质量减轻10 kg。既往:8年前发现肠息肉,间断行内镜下息肉切除术4次,4年前行开腹肠息肉切除术及胆囊切除术,7个月前行胃息
-
Key words:
- amyloidosis /
- case reports
-
[1]BESTARD MATAMOROS O, POVEDA MONJE R, IBERNON VILARM, et al.Systemic AA amyloidosis induced by benign neoplasms[J].Nefrologia, 2008, 28 (1) :93-98. [2]PERFETTO F, MOGGI-PIGNONE A, LIVI R, et al.Systemic amyloidosis:a challenge for the rheumatologist[J].Nat Rev Rheumatol, 2010, 6 (7) :417-429. [3]HU YL, PAN Y, XIN GJ, et al.Clinical diagnosis of patientswith hepatic amyloid degeneration[J].J Clin Hepatol, 2010, 26 (1) :65-66. (in Chinese) 胡玉琳, 潘煜, 辛桂杰, 等.4例肝淀粉样变性的临床特点和分析[J].临床肝胆病杂志, 2010, 26 (1) :65-66. [4]COHEN AD, COMENZO RL.Systemic light-chain amyloidosis:advances in diagnosis, prognosis, and therapy[J].Hematology Am Soc Hematol Educ Program, 2010, 2010 (1) :287-294. [5]SJOLANDER D, ROCKEN C, WESTERMARK P, et al.Establishing the fluorescent amyloid ligand h-FTAA for studying human tissues with systemic and localized amyloid[J].Amyloid, 2016, 23 (2) :98-108. [6]HUANG X, WANG Q, JIANG S, et al.The clinical featuresand outcomes of systemic AL amyloidosis:a cohort of 231 Chinese patients[J].Clin Kidney J, 2015, 8 (1) :120-126. [7]DISPENZIERI A, BUADI F, KUMAR SK, et al.Treatment of immunoglobulin light chain amyloidosis:mayo Stratification of Myeloma and Risk-Adapted Therapy (m SMART) consensus statement[J].Mayo Clin Proc, 2015, 90 (8) :1054-1081.
计量
- 文章访问数: 1540
- HTML全文浏览量: 10
- PDF下载量: 385
- 被引次数: 0