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原发性肝癌发生血管侵犯的危险因素分析

常秀娟 陆荫英 荣光华 刘泽 陈艳 许桂林 高旭东 楼敏 王春平 杨永平 曾珍

柳正植, 高振月, 任庆, 霍丹丹, 杨海淼. 恩替卡韦片在中国健康人体中的生物等效性及安全性评价[J]. 临床肝胆病杂志, 2020, 36(12): 2695-2699. DOI: 10.3969/j.issn.1001-5256.2020.12.011.
引用本文: 柳正植, 高振月, 任庆, 霍丹丹, 杨海淼. 恩替卡韦片在中国健康人体中的生物等效性及安全性评价[J]. 临床肝胆病杂志, 2020, 36(12): 2695-2699. DOI: 10.3969/j.issn.1001-5256.2020.12.011.
LIU ZhengZhi, GAO ZhenYue, REN Qing, HUO DanDan, YANG HaiMiao. Bioequivalence and safety of entecavir tablets in healthy Chinese subjects[J]. J Clin Hepatol, 2020, 36(12): 2695-2699. DOI: 10.3969/j.issn.1001-5256.2020.12.011.
Citation: LIU ZhengZhi, GAO ZhenYue, REN Qing, HUO DanDan, YANG HaiMiao. Bioequivalence and safety of entecavir tablets in healthy Chinese subjects[J]. J Clin Hepatol, 2020, 36(12): 2695-2699. DOI: 10.3969/j.issn.1001-5256.2020.12.011.

原发性肝癌发生血管侵犯的危险因素分析

DOI: 10.3969/j.issn.1001-5256.2018.05.022
基金项目: 

国家自然科学基金面上项目(81372248); 

详细信息
  • 中图分类号: R735.7

Risk factors for vascular invasion of primary liver cancer

Research funding: 

 

  • 摘要: 目的探讨影响原发性肝癌血管侵犯的危险因素。方法收集2013年1月-2014年6月于解放军第三○二医院住院的211例肝癌患者的临床资料,其中133例用于logistic回归模型拟合,78例用于该模型的检验。原发性肝癌血管侵犯影响因素分析采用单因素和多因素logistic回归分析,并建立回归模型,绘制受试者工作特征曲线(ROC曲线),确定预测血管侵犯模型的最佳临界值。结果单因素logistic回归分析显示,肿瘤直径、中性粒细胞/淋巴细胞比值(NLR)、血小板/淋巴细胞比值(PLR)、纤维蛋白原(Fb)和淋巴结转移为肝癌血管侵犯的危险因素(95%可信区间:1.3761.846、1.8474.195、1.0081.024、1.6083.274,P值均=0);经多因素logistic回归分析筛选出肿瘤直径、PLR、NLR、Fb(95%可信区间:1.2501.815、0.1731.998、1.4114.397、1.0082....

     

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  • 收稿日期:  2017-11-16
  • 出版日期:  2018-05-20
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