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原发性肝癌发生血管侵犯的危险因素分析

常秀娟 陆荫英 荣光华 刘泽 陈艳 许桂林 高旭东 楼敏 王春平 杨永平 曾珍

常秀娟, 陆荫英, 荣光华, 刘泽, 陈艳, 许桂林, 高旭东, 楼敏, 王春平, 杨永平, 曾珍. 原发性肝癌发生血管侵犯的危险因素分析[J]. 临床肝胆病杂志, 2018, 34(5): 1038-1041. DOI: 10.3969/j.issn.1001-5256.2018.05.022.
引用本文:
Chang XiuJuan, Lu YinYing, Rong GuangHua, Liu Ze, Chen Yan, Xu GuiLin, Gao XuDong, Lou Min, Wang ChunPing, Yang YongPing, Ceng Zhen. Risk factors for vascular invasion of primary liver cancer[J]. J Clin Hepatol, 2018, 34(5): 1038-1041. DOI: 10.3969/j.issn.1001-5256.2018.05.022.
Citation:

原发性肝癌发生血管侵犯的危险因素分析

DOI: 10.3969/j.issn.1001-5256.2018.05.022
基金项目: 

国家自然科学基金面上项目(81372248); 

详细信息
  • 中图分类号: R735.7

Risk factors for vascular invasion of primary liver cancer

Research funding: 

 

  • 摘要: 目的探讨影响原发性肝癌血管侵犯的危险因素。方法收集2013年1月-2014年6月于解放军第三○二医院住院的211例肝癌患者的临床资料,其中133例用于logistic回归模型拟合,78例用于该模型的检验。原发性肝癌血管侵犯影响因素分析采用单因素和多因素logistic回归分析,并建立回归模型,绘制受试者工作特征曲线(ROC曲线),确定预测血管侵犯模型的最佳临界值。结果单因素logistic回归分析显示,肿瘤直径、中性粒细胞/淋巴细胞比值(NLR)、血小板/淋巴细胞比值(PLR)、纤维蛋白原(Fb)和淋巴结转移为肝癌血管侵犯的危险因素(95%可信区间:1.3761.846、1.8474.195、1.0081.024、1.6083.274,P值均=0);经多因素logistic回归分析筛选出肿瘤直径、PLR、NLR、Fb(95%可信区间:1.2501.815、0.1731.998、1.4114.397、1.0082....

     

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  • 收稿日期:  2017-11-16
  • 出版日期:  2018-05-20
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