OX40/OX40L与慢性肝炎免疫发病机制的研究进展

秦维; 赵彩彦; 杨昭; 祝素平; 李木松; 霍玉玲

doi:10.3969/j.issn.1001-5256.2018.05.038

OX40/OX40L与慢性肝炎免疫发病机制的研究进展

DOI: 10.3969/j.issn.1001-5256.2018.05.038

保定市传染病医院肝病科

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中图分类号: R575.1
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出版历程
- 出版日期: 2018-05-20

Research advances in the role of OX40/OX40L in the immune pathogenesis of chronic hepatitis

Infectious Disease Hospital of Baoding, Baoding, Hebei 071000, China

摘要

摘要:
慢性肝炎的发生发展与人体的免疫功能强弱密切相关,其中T淋巴细胞发挥着重要作用。共刺激分子OX40/OX40L参与T淋巴细胞的活化,综述了OX40/OX40L的分子特性、参与免疫调控的机制以及与慢性肝病的关系。
- 肝炎,慢性 /
- OX40配体 /
- 肿瘤坏死因子类 /
- 免疫 /
- 综述
Abstract:
The development and progression of chronic hepatitis are closely associated with the immune function of human body, and T cells play an important role in this process. Costimulatory molecules OX40/OX40 L are involved in the activation of T cells. This article reviews the molecular features of OX40/OX40 L, the mechanism of action of OX40/OX40 L in immune regulation, and the association between OX40/OX40 L and chronic liver diseases.
- hepatitis, chronic /
- OX40 ligand /
- tumor necrosis factors /
- immunity /
- review

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参考文献(29)

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