Current status of research on primary and secondary risk factors for esophagogastric variceal rebleeding in patients with liver cirrhosis
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摘要: 肝硬化食管胃静脉曲张破裂出血的风险诸多,主要表现在门静脉高压、破裂处血栓形成及血液凝固、硬化部位或套扎点数、内环境、营养不良风险程度、Child-Pugh肝功能分级、静脉曲张程度、红色征、出血程度和门静脉内径等方面。对肝硬化食管胃静脉曲张破裂出血因素的研究现状进行了主次划分及讨论,认为肝硬化食管胃静脉曲张破裂再出血的主要因素是门静脉压力大小、破裂处血栓快速形成能力、是否急诊处理、内环境状态、营养不良风险程度和肝功能储备。Abstract: There are various risk factors for esophagogastric variceal bleeding ( EVB) in patients with liver cirrhosis, such as portal hypertension, thrombosis and blood coagulation in the ruptured blood vessel, sclerotic region or number of ligation points, internal environment, degree of risk of malnutrition, Child-Pugh class, the extent of varices, red color sign, severity of bleeding, and diameter of the portal vein.This article reviews the current status of research on risk factors for EVB in patients with liver cirrhosis and classifies such factors into primary and secondary risk factors, and it is pointed out that portal venous pressure, ability of rapid thrombosis in the ruptured blood vessel, presence or absence of emergency treatment, internal environment, degree of risk of malnutrition, and hepatic functional reserve are predominant risk factors for esophagogastric variceal rebleeding in patients with liver cirrhosis.
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Key words:
- liver cirrhosis /
- esophageal and gastric varices /
- hemorrhage /
- risk factors /
- review
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