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乙型肝炎肝硬化合并皮肌炎1例报告

李艳艳 温晓玉 张娟 高润平

引用本文:
Citation:

乙型肝炎肝硬化合并皮肌炎1例报告

DOI: 10.3969/j.issn.1001-5256.2018.12.029
详细信息
  • 中图分类号: R512.62;R575.2;R593.26

Hepatitis B cirrhosis with dermatomyositis: A case report

  • 摘要:

    <正>皮肌炎(dermatomyositis,DM)是一种伴有典型皮疹的特发性炎症性肌病。DM病因未明,目前认为遗传易感者由感染与非感染环境因素所诱发,通过免疫介导发病[1]。曾有报道HBV相关DM的病例[2],然而,并非慢性HBV感染与DM一定具有相关性。本文报道1例HBV相关肝硬化合并DM的患者。1病例资料患者男性,46岁,因"HBs Ag阳性15年,肝功异常4年,皮疹4个月、运动不灵活半月"入本院诊治。患者入院前发现HBs Ag阳性15年,自觉轻度乏力,肝功能转氨酶间歇升高4年,未行抗HBV治疗。入院前4个月无明显诱因出现面部及

     

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    [2] MASON A, THEAL J, BAIN V, et al. Hepatitis B virus replication in damaged endothelial tissues of patients with extrahepatic disease[J].AM J Gastroenterol, 2005, 100 (4) :972-976.
    [3] SHU XM, MA L, LU X, et al. Myositis disease activity tool in Chinese patients with polymyositis/dermatomyositis[J]. Natl Med China, 2011, 91 (19) :1382-1330.
    [4] WANG WY, YANG J, LU S, et al. A case of primary biliary cirrhosis complicated by dermatomyositis without dermatitis[J]. J Clin Hepatol, 2012, 31 (2) :269-272. (in Chinese) 汪维艳, 杨京, 陆爽, 等.原发性胆汁性肝硬化伴无皮炎性皮肌炎1例报告[J].临床肝胆病杂志, 2012, 31 (2) :269-272.
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    [7] KEE SJ, KIM TJ, LEE SJ, et al. Dermatomyositis associated with hepatitis B virus-related hepatocellular carcinoma[J]. Rheumatol Int, 2009, 29 (5) :959-599.
    [8] YANG SY, CHA BK, KIM G, et al. Dermatomyositis associated with hepatitis B virus-related hepatocellular carcinoma[J]. Korean J Intern Med, 2015, 29 (2) :231-235.
    [9] European Association for the Study of the Liver. EASL clinical practice guidelines:Management of chronic hepatitis B virus infection[J]. J Hepatol, 2012, 57 (1) :167-185.
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  • 出版日期:  2018-12-20
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