Hepatitis B cirrhosis with dermatomyositis: A case report
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摘要:
<正>皮肌炎(dermatomyositis,DM)是一种伴有典型皮疹的特发性炎症性肌病。DM病因未明,目前认为遗传易感者由感染与非感染环境因素所诱发,通过免疫介导发病[1]。曾有报道HBV相关DM的病例[2],然而,并非慢性HBV感染与DM一定具有相关性。本文报道1例HBV相关肝硬化合并DM的患者。1病例资料患者男性,46岁,因"HBs Ag阳性15年,肝功异常4年,皮疹4个月、运动不灵活半月"入本院诊治。患者入院前发现HBs Ag阳性15年,自觉轻度乏力,肝功能转氨酶间歇升高4年,未行抗HBV治疗。入院前4个月无明显诱因出现面部及
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Key words:
- hepatitis B, chronic /
- dermatomyositis /
- case reports
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[1] SASAKI H, KOHSAKA H. Current diagnosis and treatment of polymyositis and dermatomyositis[J]. Mod Rheumatol, 2018.[Epub ahead of print] [2] MASON A, THEAL J, BAIN V, et al. Hepatitis B virus replication in damaged endothelial tissues of patients with extrahepatic disease[J].AM J Gastroenterol, 2005, 100 (4) :972-976. [3] SHU XM, MA L, LU X, et al. Myositis disease activity tool in Chinese patients with polymyositis/dermatomyositis[J]. Natl Med China, 2011, 91 (19) :1382-1330. [4] WANG WY, YANG J, LU S, et al. A case of primary biliary cirrhosis complicated by dermatomyositis without dermatitis[J]. J Clin Hepatol, 2012, 31 (2) :269-272. (in Chinese) 汪维艳, 杨京, 陆爽, 等.原发性胆汁性肝硬化伴无皮炎性皮肌炎1例报告[J].临床肝胆病杂志, 2012, 31 (2) :269-272. [5] KEE KM, WANG JH, LEE CM, et al. Chronic hepatitis C virus infection associated with dermatomyositis and hepatocellular carcinoma[J].Chang Gung Med J, 2004, 27 (11) :834-838. [6] ANDRAS C, PONYI A, CONSTANIN T. Dermatomyositis and polymyositis associated with malignancy:A 21-year retrospective study[J]. J Rheumatol, 2008, 35 (3) :438-444. [7] KEE SJ, KIM TJ, LEE SJ, et al. Dermatomyositis associated with hepatitis B virus-related hepatocellular carcinoma[J]. Rheumatol Int, 2009, 29 (5) :959-599. [8] YANG SY, CHA BK, KIM G, et al. Dermatomyositis associated with hepatitis B virus-related hepatocellular carcinoma[J]. Korean J Intern Med, 2015, 29 (2) :231-235. [9] European Association for the Study of the Liver. EASL clinical practice guidelines:Management of chronic hepatitis B virus infection[J]. J Hepatol, 2012, 57 (1) :167-185. [10] FASANO M, LAMPERTICO P, MARZANO A. HBV DNA suppression and HBs Ag clearance in HBe Ag negative chronic hepatitis B patients on lamivudine therapy for over 5 years[J]. J Hepatol, 2012, 56 (6) :1254-1258. [11] AYGEN B, DEMIR AM, KARABAY O, et al. Immunosuppressive therapy and the risk of hepatitis B reactivation:Consensus report[J]. Turk J Gastroenterol, 2018, 29 (3) :259-269.
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