结核病合并抗-HCV阳性患者临床诊疗的常见问题

詹淑华; 陈青; 马世武

doi:10.3969/j.issn.1001-5256.2018.12.036

结核病合并抗-HCV阳性患者临床诊疗的常见问题

DOI: 10.3969/j.issn.1001-5256.2018.12.036

1. 昆明医科大学成都军区昆明总医院临床学院
2. 成都军区昆明总医院感染科

基金项目:

云南省中青年学术技术带头人项目(第十八批)；

详细信息

中图分类号: R52;R512.63
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出版历程
- 出版日期: 2018-12-20

Clinical issues in the diagnosis and treatment of tuberculosis patients with positive antibody to hepatitis C virus

Research funding:

摘要

摘要: 临床上经常会遇到结核合并抗-HCV阳性患者（TB-HCV）,其中也包含了结核患者合并HCV现症感染者,这给临床管理和诊治带来了一定的困难。介绍了国内外TB-HCV流行率情况,并逐步分析了在TB-HCV患者诊治过程中可能发生的药物相互作用、药物性肝损伤、HCV再激活和TB再激活等系列问题。认为在诊疗TB-HCV患者时应该加强管理,选择恰当的治疗方案。
- 结核 /
- 肝炎病毒属 /
- 药物相互作用 /
- 药物性肝损伤 /
- 病毒激活 /
- 综述
Abstract: Tuberculosis patients with positive antibody to hepatitis C virus (TB-HCV patients) are often seen in clinical practice, and these TB-HCV patients include those with HCV infection. That makes the clinical management and diagnosis/treatment of TB-HCV difficult. This article introduces the prevalence of TB-HCV around the world, and analyzes the potential issues in the diagnosis and treatment of TB-HCV patients, such as drug-drug interactions, drug-induced liver injury, HCV reactivation, and TB reactivation. Through this review, it is recommended that the management should be strengthened and the appropriate therapeutic regimen should be selected in the diagnosis and treatment of TB-HCV patients.
- tuberculosis /
- hepacivirus /
- drug-drug interactions /
- drug-induced liver injury /
- virus activation /
- review

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参考文献(44)

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