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他汀类药物对2型糖尿病患者发生肝细胞癌风险的影响

施凤 雷宇鹏

引用本文:
Citation:

他汀类药物对2型糖尿病患者发生肝细胞癌风险的影响

DOI: 10.3969/j.issn.1001-5256.2019.01.031
详细信息
  • 中图分类号: R735.7;R587.1

Effect of statins on hepatocellular carcinoma in patients with type 2 diabetes

  • 摘要:

    <正>肝细胞癌(HCC)为全球性疾病,其发病率在全球范围内各不相同,在北美(4. 9/100 000)和欧洲(5. 8/100 000)最低,在东亚地区(35. 5/100 000)最高,主要是因为东亚地区感染慢性乙型肝炎患者较多[1]。其致病因素包括慢性乙型肝炎或丙型肝炎、肝硬化、重度饮酒、遗传性血色素沉着症、黄曲霉毒素暴露、种族/基因组成、自身免疫性肝炎、非酒精性脂肪肝等[2-3]。其中有研究[4]发现,2型糖尿病会增加HCC的发病率,且Wang等[5]前瞻性研究表明与非糖尿病人群相比,糖尿病患者中包含

     

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