Clinical assessment of the reversal of liver cirrhosis: “Point of return”
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摘要: 目前大量临床研究已经证实,部分肝硬化可以实现逆转。因此,可准确评估肝硬化能否逆转以及何时逆转的方法成为临床研究焦点。这有助于更具有特异性地评估治疗效果,调整治疗方案以及判断预后结局等。从无创模型以及肝活组织检查等多方面,来探讨不同病因肝硬化逆转后各项指标的应用,旨在寻求更精准地反映逆转特征及手段。Abstract: Nowadays, many clinical studies have demonstrated that some patients can achieve the reversal of liver cirrhosis. Therefore, the methods for accurate assessment of whether the reversal of liver cirrhosis can be achieved and when it is achieved have become the hotspots in clinical research. This helps with the specific evaluation of therapeutic outcome, the adjustment of treatment regimen, and the prediction of prognosis. This article introduces the application of various indices after the reversal of liver cirrhosis due to different etiologies from the aspects of noninvasive models and liver biopsy, in order to search for the methods that can accurately reflect the features of reversal.
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Key words:
- liver cirrhosis /
- biological markers /
- pathology, clinical
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