Th1/Th2细胞平衡与纤维增生性疾病的相关性

黄辉; 周扬; 平键; 徐列明

doi:10.3969/j.issn.1001-5256.2019.04.039

Th1/Th2细胞平衡与纤维增生性疾病的相关性

DOI: 10.3969/j.issn.1001-5256.2019.04.039

1. 上海中医药大学附属曙光医院
2. 上海中医药大学肝病研究所
3. 上海中医药大学附属岳阳医院
4. 肝肾疾病病证教育部重点实验室

基金项目:

国家自然科学基金资助项目(8157141178)；

详细信息

中图分类号: R364
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出版历程
- 出版日期: 2019-04-20

Research advances in Th1/Th2 balance and fibrotic diseases

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

Research funding:

摘要

摘要: 机体免疫与纤维化疾病的发生存在密切联系。其中CD4+T淋巴细胞亚群的辅助性T淋巴细胞（Th） 1/Th2之间的细胞平衡在许多疾病的发生与发展中发挥着重要的调节作用。介绍了Th1/Th2细胞平衡与肝纤维化、肺纤维化及肾纤维化之间的相关性。认为除对Th1/Th2分泌的细胞因子检测外,还应对Th与其他细胞之间的具体关系及机制进行研究。
- Th1细胞 /
- Th2细胞 /
- 细胞平衡 /
- 纤维化 /
- 综述
Abstract: Body immunity is closely associated with the pathogenesis of fibrotic diseases. In CD4+ T lymphocyte subsets, T helper 1 ( Th1) /T helper 2 ( Th2) balance plays an important regulatory role in the development and progression of many diseases. This article describes the association of Th1/Th2 balance with liver fibrosis, pulmonary fibrosis, and renal fibrosis. It is believed that in addition to the measurement of single cytokines, further studies are needed to clarify the specific association between T helper cells and other cells and related mechanisms.
- Th1 cells /
- Th2 cells /
- cell balance /
- fibrosis /
- review

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参考文献(29)

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