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非酒精性脂肪性肝病肝脏微循环障碍探索

刘亚娟 李良平

丁晓燕, 陈京龙, 孙巍, 李文东, 郭晓笛, 申燕军, 孙莎莎, 庄秀芬. 射频消融先后顺序对XELOX方案治疗结直肠癌肝转移患者安全性和预后的影响[J]. 临床肝胆病杂志, 2018, 34(12): 2603-2609. DOI: 10.3969/j.issn.1001-5256.2018.12.019.
引用本文: 丁晓燕, 陈京龙, 孙巍, 李文东, 郭晓笛, 申燕军, 孙莎莎, 庄秀芬. 射频消融先后顺序对XELOX方案治疗结直肠癌肝转移患者安全性和预后的影响[J]. 临床肝胆病杂志, 2018, 34(12): 2603-2609. DOI: 10.3969/j.issn.1001-5256.2018.12.019.
Ding XiaoYan, Chen JingLong, Sun Wei, Li WenDong, Guo XiaoDi, Shen YanJun, Sun ShaSha, Zhuang XiuFen. Influence of time schedule of radiofrequency ablation on the safety and prognosis of patients with colorectal cancer liver metastasis receiving XELOX regimen: A single-center clinical study[J]. J Clin Hepatol, 2018, 34(12): 2603-2609. DOI: 10.3969/j.issn.1001-5256.2018.12.019.
Citation: Ding XiaoYan, Chen JingLong, Sun Wei, Li WenDong, Guo XiaoDi, Shen YanJun, Sun ShaSha, Zhuang XiuFen. Influence of time schedule of radiofrequency ablation on the safety and prognosis of patients with colorectal cancer liver metastasis receiving XELOX regimen: A single-center clinical study[J]. J Clin Hepatol, 2018, 34(12): 2603-2609. DOI: 10.3969/j.issn.1001-5256.2018.12.019.

非酒精性脂肪性肝病肝脏微循环障碍探索

DOI: 10.3969/j.issn.1001-5256.2019.04.046
基金项目: 

四川省卫计委重要课题(16ZD024); 

详细信息
  • 中图分类号: R575.5

Liver microcirculation disturbance in nonalcoholic fatty liver disease

Research funding: 

 

  • 摘要: 目前非酒精性脂肪性肝病发病机制尚不完全清楚,但肝脏微循环灌注改变是疾病进展的一个重要特征,其中肝细胞脂肪蓄积是导致微血管损伤的关键。介绍了正常微循环功能及结构、神经调节,着重分析了肝病微循环变化机制继而引发的微观细胞分子水平变化及宏观影像学改变。故推测,探明肝脏微循环变化可为非酒精性脂肪性肝病的病理生物学提供新见解,优化无创诊断帮助识别高危人群及早期非酒精性脂肪性肝炎患者。

     

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